Catalase-like Catalytic Activity of Ion-Exchange Resins Modified with Metalloporphyrins

Yutaka Saito; Masaki Mifune; Teruhisa Kawaguchi; Junichi Odo; Yoshimasa Tanaka; Masahiko Chikuma; Hisashi Tanaka

doi:10.1248/cpb.34.2885

Catalase-like Catalytic Activity of Ion-Exchange Resins Modified with Metalloporphyrins

Yutaka Saito, Masaki Mifune, Teruhisa Kawaguchi, Junichi Odo, Yoshimasa Tanaka, Masahiko Chikuma, Hisashi Tanaka

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

In an attempt to develop good artificial mimesis of catalase, the catalase-like catalytic activity of common ion-exchange resins modified with various metalloporphyrins was estimated in terms of their activity to accelerate in the decomposition of hydrogen peroxide. The anion exchange-resin modified with manganese-tetrakis(sulfophenyl)porphine was found to be the best. This resin retained its activity after repeated use (ten times). The presence of manganese or cobalt as a central metal ion was found to be essential for the activity.

Original language	English
Pages (from-to)	2885-2889
Number of pages	5
Journal	Chemical and Pharmaceutical Bulletin
Volume	34
Issue number	7
DOIs	https://doi.org/10.1248/cpb.34.2885
Publication status	Published - 1986

Keywords

Catalase mimesis
Catalase-like activity
hydrogen peroxide decomposition
ion-exchange resin functionalization
modified metallo-porphyrin
terfunctional reagent

ASJC Scopus subject areas

Chemistry(all)
Drug Discovery

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10.1248/cpb.34.2885

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abstract = "In an attempt to develop good artificial mimesis of catalase, the catalase-like catalytic activity of common ion-exchange resins modified with various metalloporphyrins was estimated in terms of their activity to accelerate in the decomposition of hydrogen peroxide. The anion exchange-resin modified with manganese-tetrakis(sulfophenyl)porphine was found to be the best. This resin retained its activity after repeated use (ten times). The presence of manganese or cobalt as a central metal ion was found to be essential for the activity.",

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author = "Yutaka Saito and Masaki Mifune and Teruhisa Kawaguchi and Junichi Odo and Yoshimasa Tanaka and Masahiko Chikuma and Hisashi Tanaka",

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T1 - Catalase-like Catalytic Activity of Ion-Exchange Resins Modified with Metalloporphyrins

AU - Saito, Yutaka

AU - Mifune, Masaki

AU - Kawaguchi, Teruhisa

AU - Odo, Junichi

AU - Tanaka, Yoshimasa

AU - Chikuma, Masahiko

AU - Tanaka, Hisashi

PY - 1986

Y1 - 1986

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AB - In an attempt to develop good artificial mimesis of catalase, the catalase-like catalytic activity of common ion-exchange resins modified with various metalloporphyrins was estimated in terms of their activity to accelerate in the decomposition of hydrogen peroxide. The anion exchange-resin modified with manganese-tetrakis(sulfophenyl)porphine was found to be the best. This resin retained its activity after repeated use (ten times). The presence of manganese or cobalt as a central metal ion was found to be essential for the activity.

KW - Catalase mimesis

KW - Catalase-like activity

KW - hydrogen peroxide decomposition

KW - ion-exchange resin functionalization

KW - modified metallo-porphyrin

KW - terfunctional reagent

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Catalase-like Catalytic Activity of Ion-Exchange Resins Modified with Metalloporphyrins

Abstract

Keywords

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