Cell differentiation inducers derived from thalidomide

Tomomi Noguchi; Hiroyuki Miyachi; Ryohei Katayama; Mikihiko Naito; Yuichi Hashimoto

doi:10.1016/j.bmcl.2005.05.005

Cell differentiation inducers derived from thalidomide

Tomomi Noguchi, Hiroyuki Miyachi, Ryohei Katayama, Mikihiko Naito, Yuichi Hashimoto

Faculty of Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

5-Hydroxy- and 4-amino-2-(2,6-diisopropylphenyl)-1H-isoindole-1,3-dione (5HPP-33 and 4APP-33, respectively) have been shown to possess cell differentiation-inducing activity toward human leukemia cell line HL-60.

Original language	English
Pages (from-to)	3212-3215
Number of pages	4
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	15
Issue number	13
DOIs	https://doi.org/10.1016/j.bmcl.2005.05.005
Publication status	Published - Jul 1 2005

Keywords

Cell differentiation
HL-60
Phenylphthalimide
Thalidomide

ASJC Scopus subject areas

Biochemistry
Molecular Medicine
Molecular Biology
Pharmaceutical Science
Drug Discovery
Clinical Biochemistry
Organic Chemistry

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10.1016/j.bmcl.2005.05.005

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@article{15530762f5dd4509a92459beef0e3bed,

title = "Cell differentiation inducers derived from thalidomide",

abstract = "5-Hydroxy- and 4-amino-2-(2,6-diisopropylphenyl)-1H-isoindole-1,3-dione (5HPP-33 and 4APP-33, respectively) have been shown to possess cell differentiation-inducing activity toward human leukemia cell line HL-60.",

keywords = "Cell differentiation, HL-60, Phenylphthalimide, Thalidomide",

author = "Tomomi Noguchi and Hiroyuki Miyachi and Ryohei Katayama and Mikihiko Naito and Yuichi Hashimoto",

note = "Funding Information: The work described in this paper was partially supported by Grants-in-Aid for Scientific Research from The Ministry of Education, Culture, Sports, Science and Technology, Japan, and the Japan Society for the Promotion of Science.",

year = "2005",

month = jul,

day = "1",

doi = "10.1016/j.bmcl.2005.05.005",

language = "English",

volume = "15",

pages = "3212--3215",

journal = "Bioorganic and Medicinal Chemistry Letters",

issn = "0960-894X",

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TY - JOUR

T1 - Cell differentiation inducers derived from thalidomide

AU - Noguchi, Tomomi

AU - Miyachi, Hiroyuki

AU - Katayama, Ryohei

AU - Naito, Mikihiko

AU - Hashimoto, Yuichi

N1 - Funding Information: The work described in this paper was partially supported by Grants-in-Aid for Scientific Research from The Ministry of Education, Culture, Sports, Science and Technology, Japan, and the Japan Society for the Promotion of Science.

PY - 2005/7/1

Y1 - 2005/7/1

N2 - 5-Hydroxy- and 4-amino-2-(2,6-diisopropylphenyl)-1H-isoindole-1,3-dione (5HPP-33 and 4APP-33, respectively) have been shown to possess cell differentiation-inducing activity toward human leukemia cell line HL-60.

AB - 5-Hydroxy- and 4-amino-2-(2,6-diisopropylphenyl)-1H-isoindole-1,3-dione (5HPP-33 and 4APP-33, respectively) have been shown to possess cell differentiation-inducing activity toward human leukemia cell line HL-60.

KW - Cell differentiation

KW - HL-60

KW - Phenylphthalimide

KW - Thalidomide

UR - http://www.scopus.com/inward/record.url?scp=20444406443&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=20444406443&partnerID=8YFLogxK

U2 - 10.1016/j.bmcl.2005.05.005

DO - 10.1016/j.bmcl.2005.05.005

M3 - Article

C2 - 15936192

AN - SCOPUS:20444406443

SN - 0960-894X

VL - 15

SP - 3212

EP - 3215

JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

IS - 13

ER -

Cell differentiation inducers derived from thalidomide

Abstract

Keywords

ASJC Scopus subject areas

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