TY - GEN
T1 - Cell proliferation on nano-structured titanium oxide layer prepared on titanium substrates
AU - Hayakawa, Satoshi
AU - Kawanishi, Koji
AU - Shirosaki, Yuki
AU - Osaka, Akiyoshi
PY - 2010/9/1
Y1 - 2010/9/1
N2 - Effects of nanometer-scale surface roughness of titanium oxide layer on the adhesion and proliferation of osteoblast-like cell were examined. The nano-structured titanium oxide layer was prepared on titanium substrates by chemical treatment and heat-treatment. The anatase or rutile phase of titanium oxide was formed on the titanium substrates. The surface roughness of titanium oxide layer depended on the chemical treatment time or the heat-treatment time. The average roughness (Sa) was controlled in the range from 10 to 70 nm. The cell metabolic activity increased on the substrate with limited surface roughness. It is found that cell proliferation is affected by nanometer-scale surface roughness of titanium oxide layer.
AB - Effects of nanometer-scale surface roughness of titanium oxide layer on the adhesion and proliferation of osteoblast-like cell were examined. The nano-structured titanium oxide layer was prepared on titanium substrates by chemical treatment and heat-treatment. The anatase or rutile phase of titanium oxide was formed on the titanium substrates. The surface roughness of titanium oxide layer depended on the chemical treatment time or the heat-treatment time. The average roughness (Sa) was controlled in the range from 10 to 70 nm. The cell metabolic activity increased on the substrate with limited surface roughness. It is found that cell proliferation is affected by nanometer-scale surface roughness of titanium oxide layer.
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M3 - Conference contribution
AN - SCOPUS:77956043866
SN - 9780470905487
T3 - Ceramic Transactions
SP - 205
EP - 212
BT - Advances in Bioceramics and Biotechnologies - A Collection of Papers Presented at the 8th Pacific Rim Conference on Ceramic and Glass Technology, PACRIM-8
T2 - 8th Pacific Rim Conference on Ceramic and Glass Technology, PACRIM-8
Y2 - 31 May 2009 through 5 June 2009
ER -