Cervical spine osteoradionecrosis

Masato Tanaka, Yoshihisa Sugimoto, Tomoyuki Takigawa, Yoshihiro Kimata, Toshifumi Ozaki

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Osteoradionecrosis (ORN), a well-known complication of radiotherapy in the mandibular bone, is very rare in the cervical spine. The authors report the result of a 3-year follow-up of a 63-year-old female patient with ORN of the cervical spine. The patient had a history of laryngeal carcinoma and was treated with chemotherapy and radiation therapy with a total of 120 Gy. Eight years later, she developed acute, severe neck pain due to cervical spine necrosis. The authors performed vascularized fibular bone graft and posterior pedicle screw fixation to reconstruct her cervical spine. The patient was successfully treated with surgery, and cervical alignment was preserved. She had neither neurological deficits nor severe neck pain at her final follow-up 3 years later. Delaying treatment of ORN may be life threatening, so the early diagnosis of this condition is important for patients who receive radiotherapy. Otolaryngologists and spine surgeons should understand this potential complication to speed diagnosis and treatment as early as possible.

Original languageEnglish
Pages (from-to)345-349
Number of pages5
JournalActa medica Okayama
Issue number4
Publication statusPublished - 2017


  • Cervical spine
  • Laryngeal carcinoma
  • Osteoradionecrosis
  • Radiotherapy

ASJC Scopus subject areas

  • General Biochemistry,Genetics and Molecular Biology


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