@article{eeece424e1914ff9b3876ab5c8f4124f,
title = "Characterization of Arabidopsis decapping proteins AtDCP1 and AtDCP2, which are essential for post-embryonic development",
abstract = "Although decapping is an important process in eukaryotic mRNA turnover, little is known about this process in plants. Here, we identified Arabidopsis thaliana decapping proteins AtDCP1 and AtDCP2 and showed that (I) AtDCP2 is an active decapping enzyme, (II) AtDCP1 interacts with itself, (III) AtDCP1 and AtDCP2 are localized to cytoplasmic foci (putative Arabidopsis processing body), and (IV) AtDCP1 and AtDCP2 are essential for post-embryonic development. Our findings provide new insights into the role of decapping-dependent mRNA turnover.",
keywords = "Arabidopsis thaliana, DCP1, DCP2, Decapping, Processing body, mRNA turnover",
author = "Shintaro Iwasaki and Atsushi Takeda and Hiroyasu Motose and Yuichiro Watanabe",
note = "Funding Information: We are grateful to Dr. Tetsuro Okuno, Dr. Kenzo Nakamura, and Dr. Junko Kyozuka for providing the plasmids and Dr. Kiyohisa Mizumoto for advice on the decapping assay. We thank INRA for providing dcp1-2 (FLAG_563G05) and the Salk Institute for providing dcp2-1 (SALK_000519). We are also thankful to Yoichiro Fujioka for help in the microscopic analysis, Dr. Chizuko Morita-Yamamuro for help in the Arabidopsis experiments, and Dr. Yukio Kurihara for his kind advice throughout this study. A.T. was supported by a Research Fellowship from The Japanese Society for the Promotion of Science for Young Scientists. This work was supported by a grant-in-Aid for scientific research, “Spatiotemporal Network of RNA Information Flow”, priority area (A) awarded by the Ministry of Education, Culture, Sports, Science, and Technology, Japan (No. 14035215). ",
year = "2007",
month = may,
day = "29",
doi = "10.1016/j.febslet.2007.04.051",
language = "English",
volume = "581",
pages = "2455--2459",
journal = "FEBS Letters",
issn = "0014-5793",
publisher = "Elsevier",
number = "13",
}