Chemical analysis of a novel coating material, CaTiO3-aC

Mika Okauchi-Yabuuchi, Ryo Tamamura, Noriyuki Nagaoka, Shin Takagi, Etsuo Kishimoto, Tohru Takagi, Andrea Rodriguez, Miho Inoue, Hitoshi Nagatsuka, Masaru Akao, Noriyuki Nagai

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


In the current study, we compared the recently developed CaTiO 3-amorphous carbon (CaTiO 3-aC) as a bone inducing coating material with HA from aspects of surface electric charge and solubility. CaTiO 3,-aC had negative surface electric charge similar to HA. Thus similar tissue reaction and bone inducing ability were considered to obtain. On the other hand solubility of CaTiO 3-aC coating was lower than HA. Moreover though CaTiO 3-aC itself showed low solubility, CaCO 3 was found to be included in it, and long-term slow Ca 2+ release occurred. Thus the sample was suggested to be used as an ion exchange material. When the implant using Ti/CaTiO 3-aC/HA double layer coating was developed, first bioactive state of the implant will continue due to HA character. Then even early resorption of HA occurs, bioactive state will continue due to CaTiO 3-aC layer. Therefore Ti base will not expose. This result is supposed to contribute long term success of the implant.

Original languageEnglish
Pages (from-to)115-120
Number of pages6
JournalJournal of Hard Tissue Biology
Issue number3
Publication statusPublished - 2008


  • CaTiO -aC
  • Coating material
  • Hydroxyapatite
  • Implant
  • Titanium

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Biochemistry
  • Biomaterials
  • Orthopedics and Sports Medicine
  • General Dentistry
  • Cell Biology


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