Chromosomal Localization of a Strain-Specific p53-Related Sequence in Rat (Rattus norvegicus)

Tetsuo Kunieda; Eiji Kobayashp; Hiroshi Ikadai; Tomonori Imamichi

doi:10.1538/expanim.44.301

Chromosomal Localization of a Strain-Specific p53-Related Sequence in Rat (Rattus norvegicus)

Tetsuo Kunieda, Eiji Kobayashp, Hiroshi Ikadai, Tomonori Imamichi

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Strain-specific restriction fragments hybridizing to human p53 gene cDNA, which was detected in only particular strains of inbred rat were revealed by Southern blot hybridization of DNAs of various inbred rat strains. Chromosomal location of the strain- specific fragments was determined on rat chromosome 1 between Kal and Pkc loci by linkage analysis using microsatellite marker loci. The fragments were concluded to be a novel p53-related sequence which is present in particular rat strains and absent from the remaining strains.

Original language	English
Pages (from-to)	301-305
Number of pages	5
Journal	Experimental Animals
Volume	44
Issue number	4
DOIs	https://doi.org/10.1538/expanim.44.301
Publication status	Published - 1995

Keywords

linkage map
p53
rat

ASJC Scopus subject areas

Animal Science and Zoology
Biochemistry, Genetics and Molecular Biology(all)
veterinary(all)

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10.1538/expanim.44.301

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abstract = "Strain-specific restriction fragments hybridizing to human p53 gene cDNA, which was detected in only particular strains of inbred rat were revealed by Southern blot hybridization of DNAs of various inbred rat strains. Chromosomal location of the strain- specific fragments was determined on rat chromosome 1 between Kal and Pkc loci by linkage analysis using microsatellite marker loci. The fragments were concluded to be a novel p53-related sequence which is present in particular rat strains and absent from the remaining strains.",

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AU - Kunieda, Tetsuo

AU - Kobayashp, Eiji

AU - Ikadai, Hiroshi

AU - Imamichi, Tomonori

PY - 1995

Y1 - 1995

N2 - Strain-specific restriction fragments hybridizing to human p53 gene cDNA, which was detected in only particular strains of inbred rat were revealed by Southern blot hybridization of DNAs of various inbred rat strains. Chromosomal location of the strain- specific fragments was determined on rat chromosome 1 between Kal and Pkc loci by linkage analysis using microsatellite marker loci. The fragments were concluded to be a novel p53-related sequence which is present in particular rat strains and absent from the remaining strains.

AB - Strain-specific restriction fragments hybridizing to human p53 gene cDNA, which was detected in only particular strains of inbred rat were revealed by Southern blot hybridization of DNAs of various inbred rat strains. Chromosomal location of the strain- specific fragments was determined on rat chromosome 1 between Kal and Pkc loci by linkage analysis using microsatellite marker loci. The fragments were concluded to be a novel p53-related sequence which is present in particular rat strains and absent from the remaining strains.

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KW - rat

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Chromosomal Localization of a Strain-Specific p53-Related Sequence in Rat (Rattus norvegicus)

Abstract

Keywords

ASJC Scopus subject areas

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