Citrus as a molecular contact point for co-evolution of Alternaria pathogens

Kazuya Akimitsu; Kouhei Ohtani; Takuya Shimagami; Mai Katsumoto; Chika Igarashi; Sawa Tanaka; Syu Matsuoka; Susumu Mochizuki; Takashi Tsuge; Mikihiro Yamamoto; Motoichiro Kodama; Kazuya Ichimura; Kenji Gomi

doi:10.1016/j.pmpp.2016.01.005

Citrus as a molecular contact point for co-evolution of Alternaria pathogens

Kazuya Akimitsu, Kouhei Ohtani, Takuya Shimagami, Mai Katsumoto, Chika Igarashi, Sawa Tanaka, Syu Matsuoka, Susumu Mochizuki, Takashi Tsuge, Mikihiro Yamamoto, Motoichiro Kodama, Kazuya Ichimura, Kenji Gomi

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Alternaria black rot, Alternaria leaf spot of rough lemon, and Alternaria brown spot of tangerines are three major citrus Alternaria pathogens. Citrus could be considered as a molecular contact point for host-selective toxin (HST)-mediated co-evolution of these Alternaria pathogens and susceptibility in the field. ACR-toxin is an HST produced by the rough lemon pathotype, and the target site of the toxin was identified as rough lemon mitochondria. The biosynthetic gene cluster for ACR-toxin production is on the 1.5 Mb-chromosome of the rough lemon pathotype. Another gene cluster for ACT-toxin production is located on the 1.9 Mb-chromosome of the tangerine pathotype. These TOX genes shown to have a role in ACR- or ACT-toxin biosynthesis by using gene disruption and silencing.

Original language	English
Pages (from-to)	93-96
Number of pages	4
Journal	Physiological and Molecular Plant Pathology
Volume	95
DOIs	https://doi.org/10.1016/j.pmpp.2016.01.005
Publication status	Published - Jul 1 2016

Keywords

Alternaria alternata
Co-evolution
Conditionally dispensable chromosome
Host-selective toxin
Pathogenicity

ASJC Scopus subject areas

Genetics
Plant Science

Access to Document

10.1016/j.pmpp.2016.01.005

Cite this

@article{1d1f48d9a8ff4a71a0ed8468adaa6718,

title = "Citrus as a molecular contact point for co-evolution of Alternaria pathogens",

abstract = "Alternaria black rot, Alternaria leaf spot of rough lemon, and Alternaria brown spot of tangerines are three major citrus Alternaria pathogens. Citrus could be considered as a molecular contact point for host-selective toxin (HST)-mediated co-evolution of these Alternaria pathogens and susceptibility in the field. ACR-toxin is an HST produced by the rough lemon pathotype, and the target site of the toxin was identified as rough lemon mitochondria. The biosynthetic gene cluster for ACR-toxin production is on the 1.5 Mb-chromosome of the rough lemon pathotype. Another gene cluster for ACT-toxin production is located on the 1.9 Mb-chromosome of the tangerine pathotype. These TOX genes shown to have a role in ACR- or ACT-toxin biosynthesis by using gene disruption and silencing.",

keywords = "Alternaria alternata, Co-evolution, Conditionally dispensable chromosome, Host-selective toxin, Pathogenicity",

author = "Kazuya Akimitsu and Kouhei Ohtani and Takuya Shimagami and Mai Katsumoto and Chika Igarashi and Sawa Tanaka and Syu Matsuoka and Susumu Mochizuki and Takashi Tsuge and Mikihiro Yamamoto and Motoichiro Kodama and Kazuya Ichimura and Kenji Gomi",

note = "Funding Information: The authors are deeply indebted to the late Dr. S. Nishimura, Dr. K. Kohmoto, Dr. H. Otani, and Dr. T. L. Peever for their vision, efforts, and collaboration for citrus Alternaria HST studies. This work was supported by Grants-in-Aids for Scientific Research (S) ( 21228001 for KA and 19108001 for TT), Scientific Research (A) ( 26252007 for KA and 23248007 for TT) and Scientific Research (B) ( 20380028 and 23380025 for MK) from the Japanese Society for Promotion of Sciences , Special Coordination Funds for Promoting Sciences from the Ministry of Education, Culture, Sports, Science, and Technology of Japan (TT) , and Precursory Research for Embryonic Science and Technology from Japan Science and Technology Agency (KA) . Publisher Copyright: {\textcopyright} 2016 Elsevier Ltd",

year = "2016",

month = jul,

day = "1",

doi = "10.1016/j.pmpp.2016.01.005",

language = "English",

volume = "95",

pages = "93--96",

journal = "Physiological and Molecular Plant Pathology",

issn = "0885-5765",

publisher = "Academic Press Inc.",

}

TY - JOUR

T1 - Citrus as a molecular contact point for co-evolution of Alternaria pathogens

AU - Akimitsu, Kazuya

AU - Ohtani, Kouhei

AU - Shimagami, Takuya

AU - Katsumoto, Mai

AU - Igarashi, Chika

AU - Tanaka, Sawa

AU - Matsuoka, Syu

AU - Mochizuki, Susumu

AU - Tsuge, Takashi

AU - Yamamoto, Mikihiro

AU - Kodama, Motoichiro

AU - Ichimura, Kazuya

AU - Gomi, Kenji

N1 - Funding Information: The authors are deeply indebted to the late Dr. S. Nishimura, Dr. K. Kohmoto, Dr. H. Otani, and Dr. T. L. Peever for their vision, efforts, and collaboration for citrus Alternaria HST studies. This work was supported by Grants-in-Aids for Scientific Research (S) ( 21228001 for KA and 19108001 for TT), Scientific Research (A) ( 26252007 for KA and 23248007 for TT) and Scientific Research (B) ( 20380028 and 23380025 for MK) from the Japanese Society for Promotion of Sciences , Special Coordination Funds for Promoting Sciences from the Ministry of Education, Culture, Sports, Science, and Technology of Japan (TT) , and Precursory Research for Embryonic Science and Technology from Japan Science and Technology Agency (KA) . Publisher Copyright: © 2016 Elsevier Ltd

PY - 2016/7/1

Y1 - 2016/7/1

N2 - Alternaria black rot, Alternaria leaf spot of rough lemon, and Alternaria brown spot of tangerines are three major citrus Alternaria pathogens. Citrus could be considered as a molecular contact point for host-selective toxin (HST)-mediated co-evolution of these Alternaria pathogens and susceptibility in the field. ACR-toxin is an HST produced by the rough lemon pathotype, and the target site of the toxin was identified as rough lemon mitochondria. The biosynthetic gene cluster for ACR-toxin production is on the 1.5 Mb-chromosome of the rough lemon pathotype. Another gene cluster for ACT-toxin production is located on the 1.9 Mb-chromosome of the tangerine pathotype. These TOX genes shown to have a role in ACR- or ACT-toxin biosynthesis by using gene disruption and silencing.

AB - Alternaria black rot, Alternaria leaf spot of rough lemon, and Alternaria brown spot of tangerines are three major citrus Alternaria pathogens. Citrus could be considered as a molecular contact point for host-selective toxin (HST)-mediated co-evolution of these Alternaria pathogens and susceptibility in the field. ACR-toxin is an HST produced by the rough lemon pathotype, and the target site of the toxin was identified as rough lemon mitochondria. The biosynthetic gene cluster for ACR-toxin production is on the 1.5 Mb-chromosome of the rough lemon pathotype. Another gene cluster for ACT-toxin production is located on the 1.9 Mb-chromosome of the tangerine pathotype. These TOX genes shown to have a role in ACR- or ACT-toxin biosynthesis by using gene disruption and silencing.

KW - Alternaria alternata

KW - Co-evolution

KW - Conditionally dispensable chromosome

KW - Host-selective toxin

KW - Pathogenicity

UR - http://www.scopus.com/inward/record.url?scp=84957922856&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84957922856&partnerID=8YFLogxK

U2 - 10.1016/j.pmpp.2016.01.005

DO - 10.1016/j.pmpp.2016.01.005

M3 - Article

AN - SCOPUS:84957922856

SN - 0885-5765

VL - 95

SP - 93

EP - 96

JO - Physiological and Molecular Plant Pathology

JF - Physiological and Molecular Plant Pathology

ER -

Citrus as a molecular contact point for co-evolution of Alternaria pathogens

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this