Clinical application of artificial bone in the maxillofacial region

Hideto Saijo, Ung Il Chung, Kazuyo Igawa, Yoshiyuki Mori, Daichi Chikazu, Mitsuyoshi Iino, Tsuyoshi Takato

Research output: Contribution to journalReview articlepeer-review

14 Citations (Scopus)


Hard tissue reconstruction is very useful for bony defects of the maxillofacial region. Autogenous bone, allogeneic bone, and artificial bone have been used to reconstruct maxillofacial bone; however, the use of autogenous bone involves high surgical invasiveness because of the need to harvest the bone. The use of allogeneic bone is associated with infections, raises ethical concerns, and is not widely used in Japan. Artificial bone has several advantages, including no need for bone harvesting, excellent biocompatibility, and a relatively easy surgical procedure. Use of artificial bone avoids the much greater invasiveness of harvesting bone, and several types of artificial bone have been developed. Design requirements for artificial bone include surgical manipulability, structural compatibility with the defective area, support properties, and the ability to induce bone regeneration; however, no artificial bone meeting all these requirements has yet been developed. Artificial bone is used in many patients in our medical center, and we have been active in developing the next generation of artificial bone with better properties. In this article, we present a case history and discuss the future development of artificial bone for use in maxillofacial reconstruction.

Original languageEnglish
Pages (from-to)171-176
Number of pages6
JournalJournal of Artificial Organs
Issue number4
Publication statusPublished - Dec 2008
Externally publishedYes


  • 3D model
  • Custom-made artificial bone
  • Maxillofacial reconstruction

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Biomaterials
  • Biomedical Engineering
  • Cardiology and Cardiovascular Medicine


Dive into the research topics of 'Clinical application of artificial bone in the maxillofacial region'. Together they form a unique fingerprint.

Cite this