Clinical statement on the PBC-AIH overlap 2024 The Intractable Hepato-Biliary Disease Study Group was supported by the Ministry of Health, Labor, and Welfare of Japan

The Working Group for Clinical statement on PBC-AIH overlap 2024

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Abstract

In clinical practice for autoimmune liver diseases (ALDs), hepatologists occasionally treat patients with overlap syndromes of ALDs with distinct etiologies. Among the various overlap syndromes, the pathology and epidemiology of the primary biliary cirrhosis (PBC)-autoimmune hepatitis (AIH) overlap syndrome remains elusive, with no current consensus on diagnostic and treatment strategies. In the absence of common diagnostic definitions or consensus treatment guidelines for the PBC-AIH overlap syndrome, hepatologists in Japan lack confidence in the treatment of patients with this diagnosis. To address this issue, the Intractable Hepato-Biliary Disease Study Group supported by the Ministry of Health, Labor, and Welfare of Japan assembled a Working Group to issue the Clinical Statement on the PBC-AIH Overlap Syndrome 2024 for the dissemination of consensus information.

Original languageEnglish
Pages (from-to)1-6
Number of pages6
JournalKanzo/Acta Hepatologica Japonica
Volume66
Issue number1
DOIs
Publication statusPublished - 2025

Keywords

  • autoimmune hepatitis
  • overlap syndrome
  • primary biliary cirrhosis

ASJC Scopus subject areas

  • Hepatology

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