TY - JOUR
T1 - Closure of the patent foramen ovale in patients with embolic stroke of undetermined source
T2 - A clinical expert opinion and consensus statement for the Asian-Pacific region
AU - Diener, Hans Christoph
AU - Akagi, Teiji
AU - Durongpisitkul, Kritvikrom
AU - Thomson, Viji Samuel
AU - Prabhakar, A. T.
AU - Sharpe, Ross
AU - Albers, Bert
AU - Lewalter, Thorsten
AU - Oki, Koichi
AU - Sharma, Vijay K.
N1 - Funding Information:
This expert opinion and consensus statement is based on discussions among clinical experts listed below during the Heart & Brain Summit in Bangkok, Thailand, 13?14 July 2019. All experts listed below reviewed and agreed with the final consensus manuscript. T Akagi, Okayama, Japan; JLK Chan, Hong Kong; CT Chi, Vietnam; C-C Chiu, Chang Hua, Taiwan; ASF Chui, Hong Kong; K Durongpisitkul, Bangkok, Thailand; E Harmeiwaty, Jakarta, Indonesia; D Firman, Jakarta, Indonesia; S Haifeng, Beijing, China; PK Hazra, Kolkata, India; FL Hiew, Kuala Lumpur, Malaysia; S Komonchan, Bangkok, Thailand; PX Lanh, Ho Chi Minh City, Vietnam; M-C Lin, Taichung, Taiwan; K Meemook, Bangkok, Thailand; AM Muthuppalaniappan, Kuala Lumpur, Malaysia; NHT My, Ho Chi Minh City, Vietnam; Y Nakajima, Iwate, Japan; K Oki, Tokyo, Japan; B Paul, Kolkata, India; AT Prabhakar, Vellore, India; P Puhl, Sydney, Australia; S Pumprueg, Bangkok, Thailand; DA Quoc, Ho Chi Minh City, Vietnam; V Samuel Thomson, Vellore, India; L Sanders, Melbourne, Australia; VK Sharma, Singapore; J Sharp, Sydney, Australia; R Sharpe, Gold Coast, Australia; E Tay, Singapore; NB Thang, Ho Chi Minh City, Vietnam; D Wang, Sydney, Australia; A Wong, Brisbane, Australia; X Yingqi, Jilin, China; W Zhanhang, Guangzhou, China. The author(s) disclosed receipt of the following financial support for the research, authorship and/or publication of this article: This consensus was developed during the Asian-Pacific Heart & Brain Summit meeting (13/14 July 2019, Bangkok, Thailand). Organization of this meeting was made possible by financial and logistical support by Abbott. There was no industry involvement in the consensus development process and the arrived consensus.
Publisher Copyright:
© 2020 World Stroke Organization.
PY - 2020/12
Y1 - 2020/12
N2 - Recently published long-term data from randomized controlled trials have provided evidence for the prevention of recurrent embolic stroke of undetermined source by percutaneous closure of the patent foramen ovale. However, most data were obtained from Caucasian populations and evidence on patent foramen ovale closure in Asian-Pacific patients is limited. The relative paucity in clinical data from this population, as well as the fact that Asian-Pacific patients may have higher bleeding risks than Caucasians, complicates clinical decision-making. This document, resulting from a consensus meeting of Asian-Pacific clinical experts, states the consensus among these experts about how to treat Asian-Pacific patients who had an embolic stroke of undetermined source and have a patent foramen ovale, based on currently available evidence and expert opinions. In addition, uncertainties and the need for clinical data regarding patent foramen ovale closure for prevention of recurrent embolic stroke of undetermined source in general, and specifically for Asian-Pacific patients, are identified.
AB - Recently published long-term data from randomized controlled trials have provided evidence for the prevention of recurrent embolic stroke of undetermined source by percutaneous closure of the patent foramen ovale. However, most data were obtained from Caucasian populations and evidence on patent foramen ovale closure in Asian-Pacific patients is limited. The relative paucity in clinical data from this population, as well as the fact that Asian-Pacific patients may have higher bleeding risks than Caucasians, complicates clinical decision-making. This document, resulting from a consensus meeting of Asian-Pacific clinical experts, states the consensus among these experts about how to treat Asian-Pacific patients who had an embolic stroke of undetermined source and have a patent foramen ovale, based on currently available evidence and expert opinions. In addition, uncertainties and the need for clinical data regarding patent foramen ovale closure for prevention of recurrent embolic stroke of undetermined source in general, and specifically for Asian-Pacific patients, are identified.
KW - Asian-pacific region
KW - Embolic stroke of undetermined source
KW - antithrombotic therapy
KW - consensus
KW - patent foramen ovale closure
KW - stroke prevention
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U2 - 10.1177/1747493020941658
DO - 10.1177/1747493020941658
M3 - Article
C2 - 32677579
AN - SCOPUS:85088090011
SN - 1747-4930
VL - 15
SP - 937
EP - 944
JO - International Journal of Stroke
JF - International Journal of Stroke
IS - 9
ER -