Complement depletion facilitates the infection of multiple brain tumors by an intravascular, replication-conditional herpes simplex virus mutant

Agriculture & Biology

• brain neoplasms 100%
• herpes simplex 82%
• complement 54%
• viruses 42%
• cobra venoms 38%
• mutants 37%
• infection 34%
• cyclophosphamide 20%
• glioma 14%
• neoplasm cells 9%
• rodents 9%
• therapeutics 8%
• neoplasms 8%
• brain 7%
• plasma cells 6%
• immunosuppressive agents 6%
• neutralizing antibodies 6%
• Adenoviridae 6%
• virus replication 6%
• humoral immunity 5%
• clinical trials 5%
• antibody formation 5%
• spleen 4%
• animals 4%
• intestines 4%
• heat treatment 4%
• kidneys 3%
• gene expression 3%
• liver 3%
• genome 2%
• rats 2%
• tissues 2%
• genes 1%
• cells 1%

Medicine & Life Sciences

• Simplexvirus 70%
• Brain Neoplasms 60%
• cobra venom factor 49%
• Oncolytic Viruses 36%
• Infections 30%
• Cyclophosphamide 18%
• Glioma 11%
• Rodentia 10%
• Nude Rats 9%
• Defective Viruses 9%
• Neoplasms 8%
• Herpes Simplex 7%
• Viral Genome 7%
• Virus Replication 6%
• Animals 6%
• Plasma Cells 6%
• Neutralizing Antibodies 6%
• Therapeutics 6%
• Brain 6%
• Adenoviridae 6%
• Intestines 5%
• Antibody Formation 5%
• Heterografts 5%
• Longevity 5%
• Immunosuppressive Agents 5%
• Spleen 5%
• Hot Temperature 5%
• Viruses 4%
• Clinical Trials 4%
• Gene Expression 3%
• Polymerase Chain Reaction 3%
• Kidney 3%
• Liver 3%
• In Vitro Techniques 2%
• Genes 2%