Concise synthesis of 11H-indolizino[1,2-b]quinolin-9-one by an aryl-aryl coupling reaction using Pd reagent

Takashi Harayama; Yosiaki Morikami; Akihiro Hori; Hiromi Nishioka; Hitoshi Abe; Yasuo Takeuchi

doi:10.3987/COM-03-S(P)19

Concise synthesis of 11H-indolizino[1,2-b]quinolin-9-one by an aryl-aryl coupling reaction using Pd reagent

Takashi Harayama, Yosiaki Morikami, Akihiro Hori, Hiromi Nishioka, Hitoshi Abe, Yasuo Takeuchi

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

The biaryl coupling reaction of 1-[(2-bromoquinoline-3-y1)methyl]-2(1H)-pyridinone using a catalytic amount of palladium acetate, tricyclohexylphosphine, and potassium acetate in DMF proceeded smoothly to give 11H-indolizino[1,2-b]quinolin-9-one in excellent yield.

Original language	English
Pages (from-to)	803-806
Number of pages	4
Journal	Heterocycles
Volume	62
DOIs	https://doi.org/10.3987/COM-03-S(P)19
Publication status	Published - Jan 1 2004

ASJC Scopus subject areas

Analytical Chemistry
Pharmacology
Organic Chemistry

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title = "Concise synthesis of 11H-indolizino[1,2-b]quinolin-9-one by an aryl-aryl coupling reaction using Pd reagent",

abstract = "The biaryl coupling reaction of 1-[(2-bromoquinoline-3-y1)methyl]-2(1H)-pyridinone using a catalytic amount of palladium acetate, tricyclohexylphosphine, and potassium acetate in DMF proceeded smoothly to give 11H-indolizino[1,2-b]quinolin-9-one in excellent yield.",

author = "Takashi Harayama and Yosiaki Morikami and Akihiro Hori and Hiromi Nishioka and Hitoshi Abe and Yasuo Takeuchi",

year = "2004",

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T1 - Concise synthesis of 11H-indolizino[1,2-b]quinolin-9-one by an aryl-aryl coupling reaction using Pd reagent

AU - Harayama, Takashi

AU - Morikami, Yosiaki

AU - Hori, Akihiro

AU - Nishioka, Hiromi

AU - Abe, Hitoshi

AU - Takeuchi, Yasuo

PY - 2004/1/1

Y1 - 2004/1/1

N2 - The biaryl coupling reaction of 1-[(2-bromoquinoline-3-y1)methyl]-2(1H)-pyridinone using a catalytic amount of palladium acetate, tricyclohexylphosphine, and potassium acetate in DMF proceeded smoothly to give 11H-indolizino[1,2-b]quinolin-9-one in excellent yield.

AB - The biaryl coupling reaction of 1-[(2-bromoquinoline-3-y1)methyl]-2(1H)-pyridinone using a catalytic amount of palladium acetate, tricyclohexylphosphine, and potassium acetate in DMF proceeded smoothly to give 11H-indolizino[1,2-b]quinolin-9-one in excellent yield.

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DO - 10.3987/COM-03-S(P)19

M3 - Article

AN - SCOPUS:0345828914

SN - 0385-5414

VL - 62

SP - 803

EP - 806

JO - Heterocycles

JF - Heterocycles

ER -

Concise synthesis of 11H-indolizino[1,2-b]quinolin-9-one by an aryl-aryl coupling reaction using Pd reagent

Abstract

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