Concise total synthesis of calothrixins A and B

Takumi Abe; Toshiaki Ikeda; Reiko Yanada; Minoru Ishikura

doi:10.1021/ol201107a

Concise total synthesis of calothrixins A and B

Takumi Abe, Toshiaki Ikeda, Reiko Yanada, Minoru Ishikura

Research output: Contribution to journal › Article › peer-review

62 Citations (Scopus)

Abstract

The concise total synthesis of calothrixins A and B has been accomplished by utilizing the one-pot formation of hexatriene as a key intermediate via the palladium-catalyzed tandem cyclization/cross-coupling reaction of triethyl(indol-2-yl)borate. In another key transformation, the indolo[3,2-j]phenanthridine core was prepared in high yield via Cu(I)-mediated 6π-electrocyclization.

Original language	English
Pages (from-to)	3356-3359
Number of pages	4
Journal	Organic Letters
Volume	13
Issue number	13
DOIs	https://doi.org/10.1021/ol201107a
Publication status	Published - Jul 1 2011
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/ol201107a

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AU - Ikeda, Toshiaki

AU - Yanada, Reiko

AU - Ishikura, Minoru

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Concise total synthesis of calothrixins A and B

Abstract

ASJC Scopus subject areas

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