Constituents of Geranium thunbergii SlEB. et Zucc.Xiii.1) Isolation of Water-Soluble Tannins by Centrifugal Partition Chromatography, and Biomimetic Synthesis of Elaeocarpusin

Takuo Okuda; Takao Inoue; Tsutomu Hatano; Takashi Yoshida; Tetsuro Shingu; Takao Inoue

doi:10.1248/cpb.34.4075

Constituents of Geranium thunbergii SlEB. et Zucc.Xiii.1) Isolation of Water-Soluble Tannins by Centrifugal Partition Chromatography, and Biomimetic Synthesis of Elaeocarpusin

Takuo Okuda, Takao Inoue, Tsutomu Hatano, Takashi Yoshida, Tetsuro Shingu, Takao Inoue

Research output: Contribution to journal › Article › peer-review

46 Citations (Scopus)

Abstract

A highly water-soluble polyphenolic compound, geraniinic acid A, together with elaeocarpusin which is composed of equimolar geraniin and ascorbic acid, has been isolated from Geranium thunbergii sieb. et zucc. by means of centrifugal partition chromatography and gel chromato-graphy, and the structure was elucidated on the basis of degradative and spectroscopic studies. One of these compounds, elaeocarpusin, was synthesized by condensation of geraniin and ascorbic acid; this route is considered to be biomimetic. The distribution of elaeocarpusin in various plants including Acer nikoense maxim. was also investigated.

Original language	English
Pages (from-to)	4075-4082
Number of pages	8
Journal	Chemical and Pharmaceutical Bulletin
Volume	34
Issue number	10
DOIs	https://doi.org/10.1248/cpb.34.4075
Publication status	Published - 1986

Keywords

Acer nikoense
Aceraceae
Geraniaceae
Geranium thunbergii
ascorbic acid
biomimetic synthesis
centrifugal parti
distribution
elaeocarpusin
geraniinic acid A
tion chromatography

ASJC Scopus subject areas

Chemistry(all)
Drug Discovery

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Constituents of Geranium thunbergii SlEB. et Zucc.Xiii.1) Isolation of Water-Soluble Tannins by Centrifugal Partition Chromatography, and Biomimetic Synthesis of Elaeocarpusin. / Okuda, Takuo; Inoue, Takao; Hatano, Tsutomu et al.
In: Chemical and Pharmaceutical Bulletin, Vol. 34, No. 10, 1986, p. 4075-4082.

Research output: Contribution to journal › Article › peer-review

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abstract = "A highly water-soluble polyphenolic compound, geraniinic acid A, together with elaeocarpusin which is composed of equimolar geraniin and ascorbic acid, has been isolated from Geranium thunbergii sieb. et zucc. by means of centrifugal partition chromatography and gel chromato-graphy, and the structure was elucidated on the basis of degradative and spectroscopic studies. One of these compounds, elaeocarpusin, was synthesized by condensation of geraniin and ascorbic acid; this route is considered to be biomimetic. The distribution of elaeocarpusin in various plants including Acer nikoense maxim. was also investigated.",

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T1 - Constituents of Geranium thunbergii SlEB. et Zucc.Xiii.1) Isolation of Water-Soluble Tannins by Centrifugal Partition Chromatography, and Biomimetic Synthesis of Elaeocarpusin

AU - Okuda, Takuo

AU - Inoue, Takao

AU - Hatano, Tsutomu

AU - Yoshida, Takashi

AU - Shingu, Tetsuro

AU - Inoue, Takao

PY - 1986

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AB - A highly water-soluble polyphenolic compound, geraniinic acid A, together with elaeocarpusin which is composed of equimolar geraniin and ascorbic acid, has been isolated from Geranium thunbergii sieb. et zucc. by means of centrifugal partition chromatography and gel chromato-graphy, and the structure was elucidated on the basis of degradative and spectroscopic studies. One of these compounds, elaeocarpusin, was synthesized by condensation of geraniin and ascorbic acid; this route is considered to be biomimetic. The distribution of elaeocarpusin in various plants including Acer nikoense maxim. was also investigated.

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KW - Geraniaceae

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KW - biomimetic synthesis

KW - centrifugal parti

KW - distribution

KW - elaeocarpusin

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KW - tion chromatography

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Constituents of Geranium thunbergii SlEB. et Zucc.Xiii.1) Isolation of Water-Soluble Tannins by Centrifugal Partition Chromatography, and Biomimetic Synthesis of Elaeocarpusin

Abstract

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ASJC Scopus subject areas

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