Continuous synthesis of alkyl ferulate by immobilized Candida antarctica lipase at high temperature

Yayoi Yoshida; Yukitaka Kimura; Megumi Kadota; Takuo Tsuno; Shuji Adachi

doi:10.1007/s10529-006-9113-8

Continuous synthesis of alkyl ferulate by immobilized Candida antarctica lipase at high temperature

Yayoi Yoshida, Yukitaka Kimura, Megumi Kadota, Takuo Tsuno, Shuji Adachi

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Abstract

1-Pentyl, 1-hexyl and 1-heptyl ferulates were continuously synthesized at 60-90°C using a reactor system in which a column packed with ferulic acid powders and another column packed with immobilized Candida antarctica lipase particles were connected in series. Conversions greater than 0.9 were achieved for the synthesis of the 1-hexyl and 1-heptyl ferulates at 90°C. The system could be stably operated for the 1-heptyl ferulate synthesis at 90°C for at least two weeks.

Original language	English
Pages (from-to)	1471-1474
Number of pages	4
Journal	Biotechnology Letters
Volume	28
Issue number	18
DOIs	https://doi.org/10.1007/s10529-006-9113-8
Publication status	Published - Sept 2006
Externally published	Yes

Keywords

Alkyl ferulate
Candida antarctica lipase
Ferulic acid
Flow-type reactor

ASJC Scopus subject areas

Biotechnology
Bioengineering
Applied Microbiology and Biotechnology

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10.1007/s10529-006-9113-8

Cite this

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title = "Continuous synthesis of alkyl ferulate by immobilized Candida antarctica lipase at high temperature",

abstract = "1-Pentyl, 1-hexyl and 1-heptyl ferulates were continuously synthesized at 60-90°C using a reactor system in which a column packed with ferulic acid powders and another column packed with immobilized Candida antarctica lipase particles were connected in series. Conversions greater than 0.9 were achieved for the synthesis of the 1-hexyl and 1-heptyl ferulates at 90°C. The system could be stably operated for the 1-heptyl ferulate synthesis at 90°C for at least two weeks.",

keywords = "Alkyl ferulate, Candida antarctica lipase, Ferulic acid, Flow-type reactor",

author = "Yayoi Yoshida and Yukitaka Kimura and Megumi Kadota and Takuo Tsuno and Shuji Adachi",

note = "Funding Information: Acknowledgments This study was partly supported by a Center-of-Excellent (COE) project for Microbial-Process Development Pioneering Future Production Systems and by the Brand Japan Program subsidized by the Ministry of Agriculture, Forestry and Fisheries of Japan.",

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doi = "10.1007/s10529-006-9113-8",

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volume = "28",

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TY - JOUR

T1 - Continuous synthesis of alkyl ferulate by immobilized Candida antarctica lipase at high temperature

AU - Yoshida, Yayoi

AU - Kimura, Yukitaka

AU - Kadota, Megumi

AU - Tsuno, Takuo

AU - Adachi, Shuji

N1 - Funding Information: Acknowledgments This study was partly supported by a Center-of-Excellent (COE) project for Microbial-Process Development Pioneering Future Production Systems and by the Brand Japan Program subsidized by the Ministry of Agriculture, Forestry and Fisheries of Japan.

PY - 2006/9

Y1 - 2006/9

N2 - 1-Pentyl, 1-hexyl and 1-heptyl ferulates were continuously synthesized at 60-90°C using a reactor system in which a column packed with ferulic acid powders and another column packed with immobilized Candida antarctica lipase particles were connected in series. Conversions greater than 0.9 were achieved for the synthesis of the 1-hexyl and 1-heptyl ferulates at 90°C. The system could be stably operated for the 1-heptyl ferulate synthesis at 90°C for at least two weeks.

AB - 1-Pentyl, 1-hexyl and 1-heptyl ferulates were continuously synthesized at 60-90°C using a reactor system in which a column packed with ferulic acid powders and another column packed with immobilized Candida antarctica lipase particles were connected in series. Conversions greater than 0.9 were achieved for the synthesis of the 1-hexyl and 1-heptyl ferulates at 90°C. The system could be stably operated for the 1-heptyl ferulate synthesis at 90°C for at least two weeks.

KW - Alkyl ferulate

KW - Candida antarctica lipase

KW - Ferulic acid

KW - Flow-type reactor

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SP - 1471

EP - 1474

JO - Biotechnology Letters

JF - Biotechnology Letters

IS - 18

ER -

Continuous synthesis of alkyl ferulate by immobilized Candida antarctica lipase at high temperature

Abstract

Keywords

ASJC Scopus subject areas

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