Copper(I)-catalyzed cross-coupling reaction of Alkynylsilanes with 1- chloroalkynes

Yasushi Nishihara, Kazutaka Ikegashira, Atsunori Mori, Tamejiro Hiyama

Research output: Contribution to journalArticlepeer-review

83 Citations (Scopus)


A variety of unsymmetrical 1,4-biaryl-1,3-butadiyne derivatives are synthesized by a copper(I)-catalized cross-coupling reaction of alkynylsilanes with 1-chloroalkynes in moderate to good yields. These reactions are derived from the transmetalation of an alkynyl group from silicon to copper in a polar solvent.

Original languageEnglish
Pages (from-to)4075-4078
Number of pages4
JournalTetrahedron Letters
Issue number23
Publication statusPublished - Jun 4 1998
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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