Covalent N-arylation by the pollutant 1,2-naphthoquinone activates the EGF receptor

Medicine & Life Sciences

• 1,2-naphthoquinone 100%
• Environmental Pollutants 60%
• ErbB Receptors 50%
• Vehicle Emissions 8%
• Air Pollutants 7%
• Particulate Matter 7%
• Receptor Protein-Tyrosine Kinases 6%
• Adenocarcinoma of Lung 6%
• Carcinogenesis 4%
• Cell Death 4%
• Ligands 4%
• Neoplasms 3%
• Cell Line 3%
• Mutation 3%
• Serum 2%

Chemical Compounds

• 1,2-Naphthoquinone 84%
• Environmental Pollutant 43%
• Air Pollutant 7%
• Modification 6%
• Cell Death 6%
• Covalent Bond 5%
• Electrophile 5%
• Tyrosine 5%
• Mutation 5%
• Protein 2%