COVID-19 Vaccine-Associated Lymphadenopathy Mimicking Regrowth of Axillary Lymph Node Metastasis of Lung Adenocarcinoma

Taku Noumi; Hiromi Watanabe; Kiichiro Ninomiya; Kadoaki Ohashi; Eiki Ichihara; Toshio Kubo; Go Makimoto; Yuka Kato; Masanori Fujii; Masahiro Tabata; Yoshinobu Maeda; Katsuyuki Hotta; Katsuyuki Kiura

doi:10.18926/AMO/64041

COVID-19 Vaccine-Associated Lymphadenopathy Mimicking Regrowth of Axillary Lymph Node Metastasis of Lung Adenocarcinoma

Taku Noumi, Hiromi Watanabe, Kiichiro Ninomiya, Kadoaki Ohashi, Eiki Ichihara, Toshio Kubo, Go Makimoto, Yuka Kato, Masanori Fujii, Masahiro Tabata, Yoshinobu Maeda, Katsuyuki Hotta, Katsuyuki Kiura

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

We encountered a woman with re-enlarged axillary lymph nodes during a computed tomography (CT) scan for surveillance of lung adenocarcinoma with axillary lymph node metastasis at the initial diagnosis that had shrunk with standard chemotherapy. We first suspected cancer recurrence and considered a change in the chemotherapeutic regimen. However, after careful history taking regarding the timing of her Coronavirus Disease 2019 (COVID-19) vaccination, and subsequent careful, close follow-up, radiological shrinkage suggested a strictly benign cause. Especially in lung cancer with a medical history of axillary lymph node involvement, clinicians should be aware that vaccine-associated lymphadenopathy can mimic cancer recurrence and sometimes prompt serious misjudgment regarding a current treatment course and strategy.

Original language	English
Pages (from-to)	593-596
Number of pages	4
Journal	Acta medica Okayama
Volume	76
Issue number	5
DOIs	https://doi.org/10.18926/AMO/64041
Publication status	Published - 2022

Keywords

Axillary lymphadenopathy
Case report
Covid-19 vaccination
Lung cancer

ASJC Scopus subject areas

General Biochemistry,Genetics and Molecular Biology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.18926/AMO/64041

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title = "COVID-19 Vaccine-Associated Lymphadenopathy Mimicking Regrowth of Axillary Lymph Node Metastasis of Lung Adenocarcinoma",

abstract = "We encountered a woman with re-enlarged axillary lymph nodes during a computed tomography (CT) scan for surveillance of lung adenocarcinoma with axillary lymph node metastasis at the initial diagnosis that had shrunk with standard chemotherapy. We first suspected cancer recurrence and considered a change in the chemotherapeutic regimen. However, after careful history taking regarding the timing of her Coronavirus Disease 2019 (COVID-19) vaccination, and subsequent careful, close follow-up, radiological shrinkage suggested a strictly benign cause. Especially in lung cancer with a medical history of axillary lymph node involvement, clinicians should be aware that vaccine-associated lymphadenopathy can mimic cancer recurrence and sometimes prompt serious misjudgment regarding a current treatment course and strategy.",

keywords = "Axillary lymphadenopathy, Case report, Covid-19 vaccination, Lung cancer",

author = "Taku Noumi and Hiromi Watanabe and Kiichiro Ninomiya and Kadoaki Ohashi and Eiki Ichihara and Toshio Kubo and Go Makimoto and Yuka Kato and Masanori Fujii and Masahiro Tabata and Yoshinobu Maeda and Katsuyuki Hotta and Katsuyuki Kiura",

note = "Publisher Copyright: {\textcopyright} 2022 by Okayama University Medical School.",

year = "2022",

doi = "10.18926/AMO/64041",

language = "English",

volume = "76",

pages = "593--596",

journal = "Acta medica Okayama",

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T1 - COVID-19 Vaccine-Associated Lymphadenopathy Mimicking Regrowth of Axillary Lymph Node Metastasis of Lung Adenocarcinoma

AU - Noumi, Taku

AU - Watanabe, Hiromi

AU - Ninomiya, Kiichiro

AU - Ohashi, Kadoaki

AU - Ichihara, Eiki

AU - Kubo, Toshio

AU - Makimoto, Go

AU - Kato, Yuka

AU - Fujii, Masanori

AU - Tabata, Masahiro

AU - Maeda, Yoshinobu

AU - Hotta, Katsuyuki

AU - Kiura, Katsuyuki

PY - 2022

Y1 - 2022

N2 - We encountered a woman with re-enlarged axillary lymph nodes during a computed tomography (CT) scan for surveillance of lung adenocarcinoma with axillary lymph node metastasis at the initial diagnosis that had shrunk with standard chemotherapy. We first suspected cancer recurrence and considered a change in the chemotherapeutic regimen. However, after careful history taking regarding the timing of her Coronavirus Disease 2019 (COVID-19) vaccination, and subsequent careful, close follow-up, radiological shrinkage suggested a strictly benign cause. Especially in lung cancer with a medical history of axillary lymph node involvement, clinicians should be aware that vaccine-associated lymphadenopathy can mimic cancer recurrence and sometimes prompt serious misjudgment regarding a current treatment course and strategy.

AB - We encountered a woman with re-enlarged axillary lymph nodes during a computed tomography (CT) scan for surveillance of lung adenocarcinoma with axillary lymph node metastasis at the initial diagnosis that had shrunk with standard chemotherapy. We first suspected cancer recurrence and considered a change in the chemotherapeutic regimen. However, after careful history taking regarding the timing of her Coronavirus Disease 2019 (COVID-19) vaccination, and subsequent careful, close follow-up, radiological shrinkage suggested a strictly benign cause. Especially in lung cancer with a medical history of axillary lymph node involvement, clinicians should be aware that vaccine-associated lymphadenopathy can mimic cancer recurrence and sometimes prompt serious misjudgment regarding a current treatment course and strategy.

KW - Axillary lymphadenopathy

KW - Case report

KW - Covid-19 vaccination

KW - Lung cancer

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DO - 10.18926/AMO/64041

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AN - SCOPUS:85141455988

SN - 0386-300X

VL - 76

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EP - 596

JO - Acta medica Okayama

JF - Acta medica Okayama

IS - 5

ER -

COVID-19 Vaccine-Associated Lymphadenopathy Mimicking Regrowth of Axillary Lymph Node Metastasis of Lung Adenocarcinoma

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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