Current use of silkworm larvae (Bombyx mori) as an animal model in pharmaco-medical research

Don D.aniel Nwibo; Hiroshi Hamamoto; Yasuhiko Matsumoto; Chikara Kaito; Kazuhisa Sekimizu

doi:10.5582/ddt.2015.01026

Current use of silkworm larvae (Bombyx mori) as an animal model in pharmaco-medical research

Don D.aniel Nwibo, Hiroshi Hamamoto, Yasuhiko Matsumoto, Chikara Kaito, Kazuhisa Sekimizu

Research output: Contribution to journal › Review article › peer-review

23 Citations (Scopus)

Abstract

We advocate the use of silkworm larvae, Bombyx mori, as an animal model for discovery of drug candidates. We have established several disease models using silkworms, which offer technical advantages in drug development and the study of host-pathogen interaction. This mini review briefly describes recent trends in the use of silkworm larvae as a non-mammalian model for drug discovery and it offers suggestions regarding the potential for silkworm use in pharmaceutical-biomedical research.

Original language	English
Pages (from-to)	133-135
Number of pages	3
Journal	Drug discoveries & therapeutics
Volume	9
Issue number	2
DOIs	https://doi.org/10.5582/ddt.2015.01026
Publication status	Published - Apr 1 2015
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)

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AU - Kaito, Chikara

AU - Sekimizu, Kazuhisa

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Current use of silkworm larvae (Bombyx mori) as an animal model in pharmaco-medical research

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