Cytotoxicity of a Trial Resin Composite Liner Containing TiK2F6 on Rat Dental Pulp Cells

Toshiyuki Itota, Yasuhiro Torii, Norio Sogawa, Chiharu Sogawa, Kiyoshi Inoue

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


The aim of this study was to assess the toxicological responses of a resin composite containing TiK2F6 and NaF in rat dental pulp cells. Trial resin composite liners were made, containing 3 wt% fluorides (TiK2F6 or NaF). These specimens were immersed in 5 ml of cell culture medium supplemented at 37°C for 24 hours. The eluates were used for the experiments. We judged the cytotoxicity of the samples by the cell viability. The original elute solution was serially diluted and then the medium was exchanged for the dilute medium. The cell viability at 1, 2 or 5 days after commencement of re-culturing was calculated. The viability of cells in the eluate from the resin composite liners containing TiK2F6 and NaF decreased with time. The cytotoxicity of TiK2F6 was weaker than that of NaF at all times.

Original languageEnglish
Pages (from-to)271-277
Number of pages7
JournalDental materials journal
Issue number3
Publication statusPublished - 1999
Externally publishedYes


  • Composite resin
  • Cytotoxicity
  • TiKF

ASJC Scopus subject areas

  • Ceramics and Composites
  • General Dentistry


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