Damage to cultivated Japanese pearl oysters by oxidative stress that was related to "mass mortality"

Yuushi Uchimura; Hirofumi Yamashita; Makoto Kuramoto; Kohji Ishihara; Manabu Sugimoto; Nobuyoshi Nakajima

doi:10.1271/bbb.67.2470

Damage to cultivated Japanese pearl oysters by oxidative stress that was related to "mass mortality"

Yuushi Uchimura
, Hirofumi Yamashita
, Makoto Kuramoto
, Kohji Ishihara
, Manabu Sugimoto
, Nobuyoshi Nakajima

Institute of Plant Science and Resources

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Increased blood-DNA breakage was observed in diseased pearl oysters. They showed significant formation of 8-hydroxydeoxyguanosine (8-OHdG) and malondialdehyde (MDA), whereas the oysters that had a low mortality rate from the disease had high activity of superoxide dismutase (SOD) and low amounts of 8-OHdG and MDA. These results suggest that radical damage had occurred only in the diseased pearl oysters with the cytolysis of their haemocytes, which was related to the mass mortality of the Japanese pearl oysters.

Original language	English
Pages (from-to)	2470-2473
Number of pages	4
Journal	Bioscience, Biotechnology and Biochemistry
Volume	67
Issue number	11
DOIs	https://doi.org/10.1271/bbb.67.2470
Publication status	Published - Nov 2003

Keywords

8-hydroxydeoxyguanosine (8-OHdG)
Malondialdehyde (MDA)
Oxidative stress
Pearl oyster
Superoxide dismutase (SOD)

ASJC Scopus subject areas

Biotechnology
Analytical Chemistry
Biochemistry
Applied Microbiology and Biotechnology
Molecular Biology
Organic Chemistry

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10.1271/bbb.67.2470

Cite this

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title = "Damage to cultivated Japanese pearl oysters by oxidative stress that was related to {"}mass mortality{"}",

abstract = "Increased blood-DNA breakage was observed in diseased pearl oysters. They showed significant formation of 8-hydroxydeoxyguanosine (8-OHdG) and malondialdehyde (MDA), whereas the oysters that had a low mortality rate from the disease had high activity of superoxide dismutase (SOD) and low amounts of 8-OHdG and MDA. These results suggest that radical damage had occurred only in the diseased pearl oysters with the cytolysis of their haemocytes, which was related to the mass mortality of the Japanese pearl oysters.",

keywords = "8-hydroxydeoxyguanosine (8-OHdG), Malondialdehyde (MDA), Oxidative stress, Pearl oyster, Superoxide dismutase (SOD)",

author = "Yuushi Uchimura and Hirofumi Yamashita and Makoto Kuramoto and Kohji Ishihara and Manabu Sugimoto and Nobuyoshi Nakajima",

note = "Funding Information: This work was supported in part by the National Research Institute of Aquaculture, Fisheries Research Agency, Japan.",

year = "2003",

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doi = "10.1271/bbb.67.2470",

language = "English",

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TY - JOUR

T1 - Damage to cultivated Japanese pearl oysters by oxidative stress that was related to "mass mortality"

AU - Uchimura, Yuushi

AU - Yamashita, Hirofumi

AU - Kuramoto, Makoto

AU - Ishihara, Kohji

AU - Sugimoto, Manabu

AU - Nakajima, Nobuyoshi

N1 - Funding Information: This work was supported in part by the National Research Institute of Aquaculture, Fisheries Research Agency, Japan.

PY - 2003/11

Y1 - 2003/11

N2 - Increased blood-DNA breakage was observed in diseased pearl oysters. They showed significant formation of 8-hydroxydeoxyguanosine (8-OHdG) and malondialdehyde (MDA), whereas the oysters that had a low mortality rate from the disease had high activity of superoxide dismutase (SOD) and low amounts of 8-OHdG and MDA. These results suggest that radical damage had occurred only in the diseased pearl oysters with the cytolysis of their haemocytes, which was related to the mass mortality of the Japanese pearl oysters.

AB - Increased blood-DNA breakage was observed in diseased pearl oysters. They showed significant formation of 8-hydroxydeoxyguanosine (8-OHdG) and malondialdehyde (MDA), whereas the oysters that had a low mortality rate from the disease had high activity of superoxide dismutase (SOD) and low amounts of 8-OHdG and MDA. These results suggest that radical damage had occurred only in the diseased pearl oysters with the cytolysis of their haemocytes, which was related to the mass mortality of the Japanese pearl oysters.

KW - 8-hydroxydeoxyguanosine (8-OHdG)

KW - Malondialdehyde (MDA)

KW - Oxidative stress

KW - Pearl oyster

KW - Superoxide dismutase (SOD)

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UR - https://www.scopus.com/pages/publications/3242884195#tab=citedBy

U2 - 10.1271/bbb.67.2470

DO - 10.1271/bbb.67.2470

M3 - Article

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AN - SCOPUS:3242884195

SN - 0916-8451

VL - 67

SP - 2470

EP - 2473

JO - Bioscience, Biotechnology and Biochemistry

JF - Bioscience, Biotechnology and Biochemistry

IS - 11

ER -

Damage to cultivated Japanese pearl oysters by oxidative stress that was related to "mass mortality"

Abstract

Keywords

ASJC Scopus subject areas

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