TY - JOUR
T1 - Detection of Epstein-Barr virus genes in malignant lymphoma with clinical and histologic features of cytophagic histiocytic panniculitis
AU - Harada, Hiroshi
AU - Iwatsuki, Keiji
AU - Kaneko, Fumio
PY - 1994
Y1 - 1994
N2 - T-cell proliferative disorders are occasionally associated with Epstein-Barr virus (EBV) infection. This study was designed to assess the clinical features of cutaneous lymphomas positivefor EBV genes. Polymerase chain reaction was used to detect EB V genes in tissue or blood samples from patients with malignant lymphoma or related diseases. Of 26 DNA samples tested, EBV genes were detected in two samples, both of which were obtained from the same patient with subcutaneous T-cell lymphoma showing clinical and histologic features of cytophagic histiocytic panniculitis. On the basis of these findings, we conclude that EBV infection may be related to cutaneous lymphoma with hemophagocytic manifestations. (J Am Acad Dermatol 1994;31:379-83.)
AB - T-cell proliferative disorders are occasionally associated with Epstein-Barr virus (EBV) infection. This study was designed to assess the clinical features of cutaneous lymphomas positivefor EBV genes. Polymerase chain reaction was used to detect EB V genes in tissue or blood samples from patients with malignant lymphoma or related diseases. Of 26 DNA samples tested, EBV genes were detected in two samples, both of which were obtained from the same patient with subcutaneous T-cell lymphoma showing clinical and histologic features of cytophagic histiocytic panniculitis. On the basis of these findings, we conclude that EBV infection may be related to cutaneous lymphoma with hemophagocytic manifestations. (J Am Acad Dermatol 1994;31:379-83.)
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U2 - 10.1016/S0190-9622(94)70177-6
DO - 10.1016/S0190-9622(94)70177-6
M3 - Article
C2 - 8034809
AN - SCOPUS:0027984741
SN - 0190-9622
VL - 31
SP - 379
EP - 383
JO - Journal of the American Academy of Dermatology
JF - Journal of the American Academy of Dermatology
IS - 2
ER -