TY - JOUR
T1 - Detection of human α-defensin-1, an antimicrobial peptide, in the fluid of jaw cysts
AU - Mizukawa, Nobuyoshi
AU - Sugiyama, Katsumi
AU - Ueno, Takaaki
AU - Mishima, Katsuaki
AU - Takagi, Shin
AU - Sugahara, Toshio
PY - 2000
Y1 - 2000
N2 - Objective. The purpose of this study was to isolate and to identify an antimicrobial peptide, human α-defensin-1 (HNP-1) in jaw cyst fluid. Study design. We collected jaw cyst fluid from 22 patients with various jaw cysts and analyzed the peptide components of them by reversed-phase high-performance liquid chromatography (HPLC). HNP-1 in the jaw cyst fluid was identified by the amino acid sequence and the molecular weight. The concentration of HNP-1 in the fluid of various jaw cysts was quantified by HPLC. Results. HNP-1 in the jaw cyst fluid was isolated, purified, and identified. The concentrations of HNP-1 in the jaw cyst fluid ranged from 27.0 to 3725.4 μg/mL. Conclusion. HNP-1 was detected in the fluid of various types of jaw cysts.
AB - Objective. The purpose of this study was to isolate and to identify an antimicrobial peptide, human α-defensin-1 (HNP-1) in jaw cyst fluid. Study design. We collected jaw cyst fluid from 22 patients with various jaw cysts and analyzed the peptide components of them by reversed-phase high-performance liquid chromatography (HPLC). HNP-1 in the jaw cyst fluid was identified by the amino acid sequence and the molecular weight. The concentration of HNP-1 in the fluid of various jaw cysts was quantified by HPLC. Results. HNP-1 in the jaw cyst fluid was isolated, purified, and identified. The concentrations of HNP-1 in the jaw cyst fluid ranged from 27.0 to 3725.4 μg/mL. Conclusion. HNP-1 was detected in the fluid of various types of jaw cysts.
UR - http://www.scopus.com/inward/record.url?scp=0034222453&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0034222453&partnerID=8YFLogxK
U2 - 10.1067/moe.2000.107055
DO - 10.1067/moe.2000.107055
M3 - Article
C2 - 10884640
AN - SCOPUS:0034222453
SN - 1079-2104
VL - 90
SP - 78
EP - 81
JO - Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
JF - Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
IS - 1
M1 - 02982
ER -