Diagnosing pancreatic tumors using contrast-enhanced harmonic endoscopic ultrasonography with Sonazoid

Naoki Yamamoto; Hironari Kato; Sho Mizukawa; Shinichiro Muro; Yutaka Akimoto; Daisuke Uchida; Takeshi Tomoda; Kazuyuki Matsumoto; Shigeru Horiguchi; Koichiro Tsutsumi; Hiroyuki Okada

Diagnosing pancreatic tumors using contrast-enhanced harmonic endoscopic ultrasonography with Sonazoid

Naoki Yamamoto, Hironari Kato, Sho Mizukawa, Shinichiro Muro, Yutaka Akimoto, Daisuke Uchida, Takeshi Tomoda, Kazuyuki Matsumoto, Shigeru Horiguchi, Koichiro Tsutsumi, Hiroyuki Okada

Research output: Contribution to journal › Article › peer-review

Abstract

Contrast-enhanced harmonic endoscopic ultrasonography (CH-EUS) with contrast agent enabled us to assess the hemodynamics closely, despite limited data in pancreatic tumors. We have initiated a prospective, single arm, and non-randomized study to clarify the accuracy and safety of CH-EUS with Sonazoid and time-intensity curve (TIC) analysis for diagnosing benign or malignant pancreatic tumors. A total of 200 patients will undergo CH-EUS and TIC analysis. Receiver operating characteristic (ROC) analysis will be used to determine the optimal parameter cutoff values for TIC analysis. This will clarify whether CH-EUS and TIC can further improve the diagnosis of pancreatic tumors over conventional EUS.

Original language	English
Pages (from-to)	323-326
Number of pages	4
Journal	Acta medica Okayama
Volume	70
Issue number	4
Publication status	Published - 2016

Keywords

CH-EUS
Pancreatic tumor
TIC

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

Cite this

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title = "Diagnosing pancreatic tumors using contrast-enhanced harmonic endoscopic ultrasonography with Sonazoid",

abstract = "Contrast-enhanced harmonic endoscopic ultrasonography (CH-EUS) with contrast agent enabled us to assess the hemodynamics closely, despite limited data in pancreatic tumors. We have initiated a prospective, single arm, and non-randomized study to clarify the accuracy and safety of CH-EUS with Sonazoid and time-intensity curve (TIC) analysis for diagnosing benign or malignant pancreatic tumors. A total of 200 patients will undergo CH-EUS and TIC analysis. Receiver operating characteristic (ROC) analysis will be used to determine the optimal parameter cutoff values for TIC analysis. This will clarify whether CH-EUS and TIC can further improve the diagnosis of pancreatic tumors over conventional EUS.",

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AU - Yamamoto, Naoki

AU - Kato, Hironari

AU - Mizukawa, Sho

AU - Muro, Shinichiro

AU - Akimoto, Yutaka

AU - Uchida, Daisuke

AU - Tomoda, Takeshi

AU - Matsumoto, Kazuyuki

AU - Horiguchi, Shigeru

AU - Tsutsumi, Koichiro

AU - Okada, Hiroyuki

PY - 2016

Y1 - 2016

N2 - Contrast-enhanced harmonic endoscopic ultrasonography (CH-EUS) with contrast agent enabled us to assess the hemodynamics closely, despite limited data in pancreatic tumors. We have initiated a prospective, single arm, and non-randomized study to clarify the accuracy and safety of CH-EUS with Sonazoid and time-intensity curve (TIC) analysis for diagnosing benign or malignant pancreatic tumors. A total of 200 patients will undergo CH-EUS and TIC analysis. Receiver operating characteristic (ROC) analysis will be used to determine the optimal parameter cutoff values for TIC analysis. This will clarify whether CH-EUS and TIC can further improve the diagnosis of pancreatic tumors over conventional EUS.

AB - Contrast-enhanced harmonic endoscopic ultrasonography (CH-EUS) with contrast agent enabled us to assess the hemodynamics closely, despite limited data in pancreatic tumors. We have initiated a prospective, single arm, and non-randomized study to clarify the accuracy and safety of CH-EUS with Sonazoid and time-intensity curve (TIC) analysis for diagnosing benign or malignant pancreatic tumors. A total of 200 patients will undergo CH-EUS and TIC analysis. Receiver operating characteristic (ROC) analysis will be used to determine the optimal parameter cutoff values for TIC analysis. This will clarify whether CH-EUS and TIC can further improve the diagnosis of pancreatic tumors over conventional EUS.

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KW - Pancreatic tumor

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Diagnosing pancreatic tumors using contrast-enhanced harmonic endoscopic ultrasonography with Sonazoid

Abstract

Keywords

ASJC Scopus subject areas

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