Difference in protein adsorption onto polymer films with or without thermal annealing

Takaaki Date, Yuko Ueda, Hironori Atarashi, Toshiki Sawada, Hideyo Matsuzawa, Keiji Tanaka, Takeshi Serizawa

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


Protein adsorptions onto non-annealed (NA) and thermally annealed (TA) polyetherimide films were examined by surface plasmon resonance measurements. Proteins adsorbed onto the NA films with smaller adsorption constants in comparison with the TA films. Neutron reflectivity measurements of the two films suggested that the outermost region of the NA films swelled with larger amounts of water molecules than the TA films. It is plausible that the aforementioned difference in the protein adsorption properties is derived from the difference in the interfacial aggregation structures of the two films.

Original languageEnglish
Pages (from-to)3106-3111
Number of pages6
JournalJournal of Nanoscience and Nanotechnology
Issue number4
Publication statusPublished - Apr 1 2014
Externally publishedYes


  • Adsorption Constant
  • Interfacial Aggregation Structure
  • Polymer Film
  • Protein Adsorption
  • Thermal Annealing

ASJC Scopus subject areas

  • Bioengineering
  • Chemistry(all)
  • Biomedical Engineering
  • Materials Science(all)
  • Condensed Matter Physics


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