Dissecting the left heart hypoplasia by pluripotent stem cells

Junko Kobayashi; Shunji Sano; Hidemasa Oh

doi:10.1007/978-4-431-54628-3_47

Dissecting the left heart hypoplasia by pluripotent stem cells

Junko Kobayashi, Shunji Sano, Hidemasa Oh

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Citation (Scopus)

Abstract

The genetic background of hypoplastic left heart syndrome (HLHS) is still unknown. Cardiac differentiation from pluripotent stem cells (PSCs) can recapitulate the cardiogenesis in vitro, and PSC technology could be useful to dissect the diseases with the complex mechanisms. In the past few years, some researches were reported to seek the pathogenesis of HLHS by using PSCs. This paper reports the achievements.

Original language	English
Title of host publication	Etiology and Morphogenesis of Congenital Heart Disease
Subtitle of host publication	From Gene Function and Cellular Interaction to Morphology
Publisher	Springer Japan
Pages	337-339
Number of pages	3
ISBN (Electronic)	9784431546283
ISBN (Print)	9784431546276
DOIs	https://doi.org/10.1007/978-4-431-54628-3_47
Publication status	Published - Jan 1 2016

Keywords

Disease modeling
Hypoplastic left heart syndrome
Pluripotent stem cells

ASJC Scopus subject areas

Medicine(all)
Biochemistry, Genetics and Molecular Biology(all)

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10.1007/978-4-431-54628-3_47

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Dissecting the left heart hypoplasia by pluripotent stem cells

Abstract

Keywords

ASJC Scopus subject areas

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