Distribution of two kinds of cystathionine γ-synthase in various bacteria

Hiroshi Kanzaki, Michihiko Kobayashi, Toru Nagasawa, Hideaki Yamada

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)


The substrate specificity of cystathionine γ-synthase (EC in various bacteria was examined.O-Succinyl-l-homoserine was used preferably as a substrate by facultative anaerobic Gram-negative bacteria belonging to such genera asEscherichia, Klebsiella, Enterobacter, Citrobacter, Erwinia, Serratia, Proteus andSalmonella. Among Gram-negative aerobic bacteria, bacteria belonging to the generaPseudomonas, Xanthomonas andAlcaligenes also usedO-succinyl-l-homoserine in preference toO-acetyl-l-homoserine. On the other hand, bacteria belonging to the generaAgrobacterium andFlavobacterium usedO-acetyl-l-homoserine preferably. As to Gram-positive aerobic bacteria, bacteria of the genusBacillus usedO-acetyl-l-homoserine exclusively. Bacteria belonging to the generaMicrococcus, Corynebacterium, Brevibacterium andArthrobacter used bothO-acetyl- andO-succinyl-l-homoserine to similar extents.

Original languageEnglish
Pages (from-to)65-68
Number of pages4
JournalFEMS Microbiology Letters
Issue number1
Publication statusPublished - Jan 1986
Externally publishedYes


  • O-Succinyl-l-homoserine
  • O-acetyl-l-homoserine

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology
  • Genetics


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