Dramatic Response to Carboplatin plus Paclitaxel in Pancreatic Mucinous Cystadenocarcinoma with Liver Metastasis

Naohiro Oda; Masahiro Tabata; Masatoshi Uno; Yuzo Umeda; Hironari Kato; Toshio Kubo; Satoru Senoo; Takahito Yagi; Toshiyoshi Fujiwara; Yoshinobu Maeda; Katsuyuki Kiura

doi:10.2169/internalmedicine.6730-20

Dramatic Response to Carboplatin plus Paclitaxel in Pancreatic Mucinous Cystadenocarcinoma with Liver Metastasis

Naohiro Oda, Masahiro Tabata, Masatoshi Uno, Yuzo Umeda, Hironari Kato, Toshio Kubo, Satoru Senoo, Takahito Yagi, Toshiyoshi Fujiwara, Yoshinobu Maeda, Katsuyuki Kiura

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Abstract

Mucinous cystic neoplasm (MCN) of the pancreas is a rare cystic tumor occurring in the pancreatic body and tail in young to middle-aged women that is pathologically characterized by an ovarian-like stroma. Chemotherapy for recurrent/advanced pancreatic MCN has been based on chemotherapy regimens for pancreatic ductal adenocarcinoma, but the prognosis is poor. We herein report a 37-year-old woman with pancreatic mucinous cystadenocarcinoma with liver metastasis that responded dramatically to carboplatin plus paclitaxel therapy (CBDCA+PTX). CBDCA+PTX may be a treatment option for recurrent/advanced pancreatic MCN with an ovarian-like stroma.

Original language	English
Pages (from-to)	2967-2971
Number of pages	5
Journal	Internal Medicine
Volume	60
Issue number	18
DOIs	https://doi.org/10.2169/internalmedicine.6730-20
Publication status	Published - 2021

Keywords

Carboplatin
Mucinous cystadenocarcinoma
Paclitaxel
Pancreas

ASJC Scopus subject areas

Internal Medicine

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10.2169/internalmedicine.6730-20

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title = "Dramatic Response to Carboplatin plus Paclitaxel in Pancreatic Mucinous Cystadenocarcinoma with Liver Metastasis",

abstract = "Mucinous cystic neoplasm (MCN) of the pancreas is a rare cystic tumor occurring in the pancreatic body and tail in young to middle-aged women that is pathologically characterized by an ovarian-like stroma. Chemotherapy for recurrent/advanced pancreatic MCN has been based on chemotherapy regimens for pancreatic ductal adenocarcinoma, but the prognosis is poor. We herein report a 37-year-old woman with pancreatic mucinous cystadenocarcinoma with liver metastasis that responded dramatically to carboplatin plus paclitaxel therapy (CBDCA+PTX). CBDCA+PTX may be a treatment option for recurrent/advanced pancreatic MCN with an ovarian-like stroma.",

keywords = "Carboplatin, Mucinous cystadenocarcinoma, Paclitaxel, Pancreas",

author = "Naohiro Oda and Masahiro Tabata and Masatoshi Uno and Yuzo Umeda and Hironari Kato and Toshio Kubo and Satoru Senoo and Takahito Yagi and Toshiyoshi Fujiwara and Yoshinobu Maeda and Katsuyuki Kiura",

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year = "2021",

doi = "10.2169/internalmedicine.6730-20",

language = "English",

volume = "60",

pages = "2967--2971",

journal = "Internal Medicine",

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TY - JOUR

T1 - Dramatic Response to Carboplatin plus Paclitaxel in Pancreatic Mucinous Cystadenocarcinoma with Liver Metastasis

AU - Oda, Naohiro

AU - Tabata, Masahiro

AU - Uno, Masatoshi

AU - Umeda, Yuzo

AU - Kato, Hironari

AU - Kubo, Toshio

AU - Senoo, Satoru

AU - Yagi, Takahito

AU - Fujiwara, Toshiyoshi

AU - Maeda, Yoshinobu

AU - Kiura, Katsuyuki

PY - 2021

Y1 - 2021

N2 - Mucinous cystic neoplasm (MCN) of the pancreas is a rare cystic tumor occurring in the pancreatic body and tail in young to middle-aged women that is pathologically characterized by an ovarian-like stroma. Chemotherapy for recurrent/advanced pancreatic MCN has been based on chemotherapy regimens for pancreatic ductal adenocarcinoma, but the prognosis is poor. We herein report a 37-year-old woman with pancreatic mucinous cystadenocarcinoma with liver metastasis that responded dramatically to carboplatin plus paclitaxel therapy (CBDCA+PTX). CBDCA+PTX may be a treatment option for recurrent/advanced pancreatic MCN with an ovarian-like stroma.

AB - Mucinous cystic neoplasm (MCN) of the pancreas is a rare cystic tumor occurring in the pancreatic body and tail in young to middle-aged women that is pathologically characterized by an ovarian-like stroma. Chemotherapy for recurrent/advanced pancreatic MCN has been based on chemotherapy regimens for pancreatic ductal adenocarcinoma, but the prognosis is poor. We herein report a 37-year-old woman with pancreatic mucinous cystadenocarcinoma with liver metastasis that responded dramatically to carboplatin plus paclitaxel therapy (CBDCA+PTX). CBDCA+PTX may be a treatment option for recurrent/advanced pancreatic MCN with an ovarian-like stroma.

KW - Carboplatin

KW - Mucinous cystadenocarcinoma

KW - Paclitaxel

KW - Pancreas

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SP - 2967

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JO - Internal Medicine

JF - Internal Medicine

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ER -

Dramatic Response to Carboplatin plus Paclitaxel in Pancreatic Mucinous Cystadenocarcinoma with Liver Metastasis

Abstract

Keywords

ASJC Scopus subject areas

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