Dye-coupling of melanocytes with endothelial cells and pericytes in the cochlea of gerbils

Shunji Takeuchi, Motonori Ando

Research output: Contribution to journalArticlepeer-review

46 Citations (Scopus)


Intercellular connections via gap junctions in the stria vascularis, which constitutes the lateral wall of the cochlear duct, were investigated by the Lucifer yellow microinjection method with the aid of a confocal laser microscope. The dye injected into an intermediate cell (melanocyte) diffused into capillary endothelial cells and pericytes as well as other intermediate cells, basal cells, and fibrocytes in the spiral ligament; whereas the dye injected into a marginal cell (epithelial cell) was confined to the injected cell. The observation of dye-coupling between intermediate cells and endothelial cells and pericytes makes likely the possibility that these cells work together to play a role in the specific function of the stria vascularis (i.e., production of the positive endocochlear potential and the endolymph) and adds endothelial cells and pericytes to the current 'two-cell model' of the stria vascularis.

Original languageEnglish
Pages (from-to)271-275
Number of pages5
JournalCell and Tissue Research
Issue number2
Publication statusPublished - 1998
Externally publishedYes


  • Gap junction
  • Gerbil
  • Intermediate cell
  • Lucifer yellow
  • Microinjection
  • Stria vascularis

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology
  • Cell Biology


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