TY - GEN
T1 - Effect of electrical stimulus intensity to hempdynamic responses of somatosensory cortex
AU - Takata, Hirotsugu
AU - Xu, Mingdi
AU - Hayami, Takehito
AU - Iramina, Keiji
PY - 2007/12/1
Y1 - 2007/12/1
N2 - To investigate the relationships between neuronal activity and hemodynamics, regional changes of hemoglobin concentration associated with cortical activation in the primary somatosensory cortex (SI) to the electrical stimulation were investigated by near-infrared spectroscopy (NIRS). We measured the hemodynamic evoked responses to the electrical stimuli of some intensities applied on the right thumb. NIRS measurements were performed on 3 healthy right-handed volunteers and we investigated the spatial and temporal features and the magnitude of the optical signal induced by cerebral activation. In this study, we consistently found that an increase in the cerebral concentration of oxygenated hemoglobin [oxy-Hb], and that a decrease in the cerebral concentration of deoxygenated hemoglobin [deoxy-Hb] at somatosensory area. Moreover, as the intensity of electrical stimuli changes stronger from 3 times to 6 times intensity of the sensory threshold of thumb, the increment of [oxy-Hb] and [total-Hb] are augmented.
AB - To investigate the relationships between neuronal activity and hemodynamics, regional changes of hemoglobin concentration associated with cortical activation in the primary somatosensory cortex (SI) to the electrical stimulation were investigated by near-infrared spectroscopy (NIRS). We measured the hemodynamic evoked responses to the electrical stimuli of some intensities applied on the right thumb. NIRS measurements were performed on 3 healthy right-handed volunteers and we investigated the spatial and temporal features and the magnitude of the optical signal induced by cerebral activation. In this study, we consistently found that an increase in the cerebral concentration of oxygenated hemoglobin [oxy-Hb], and that a decrease in the cerebral concentration of deoxygenated hemoglobin [deoxy-Hb] at somatosensory area. Moreover, as the intensity of electrical stimuli changes stronger from 3 times to 6 times intensity of the sensory threshold of thumb, the increment of [oxy-Hb] and [total-Hb] are augmented.
KW - Electrical stimuli
KW - Hemodynamic responses
KW - Near-infrared spectroscopy (NIRS)
KW - Somatosensory cortex
UR - http://www.scopus.com/inward/record.url?scp=48049117130&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=48049117130&partnerID=8YFLogxK
U2 - 10.1109/NFSI-ICFBI.2007.4387752
DO - 10.1109/NFSI-ICFBI.2007.4387752
M3 - Conference contribution
AN - SCOPUS:48049117130
SN - 1424409489
SN - 9781424409488
T3 - Proc. of 2007 Joint Meet. of the 6th Int. Symp. on Noninvasive Functional Source Imaging of the Brain and Heart and the Int. Conf. on Functional Biomedical Imaging, NFSI and ICFBI 2007
SP - 280
EP - 282
BT - Proc. of 2007 Joint Meet. of the 6th Int. Symp. on Noninvasive Functional Source Imaging of the Brain and Heart and the Int. Conf. on Functional Biomedical Imaging, NFSI and ICFBI 2007
T2 - 2007 Joint Meeting of the 6th International Symposium on Noninvasive Functional Source Imaging of the Brain and Heart and the International Conference on Functional Biomedical Imaging, NFSI and ICFBI 2007
Y2 - 12 October 2007 through 14 October 2007
ER -