Effects of Endoluminal Stent-Grafts on Acute Aortic Dissection in Dogs

Keiji Yunoki, Hatuzo Uchida, Shunji Sano, Nobuyoshi Shimizu

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


Acute aortic dissection is a life-threatening condition, and may be treated with aggressive hypotensive drug therapy, but emergency surgery is often necessary. We evaluated the effectiveness of stent-grafts for the treatment of acute aortic dissection. Aortic dissection was surgically created in the descending thoracic aorta in 20 adult mongrel dogs. A stent-graft was inserted in the entry position. The tested animals were divided into 4 groups based on re-entry type and blood pressure alteration rate (AR) after acute aortic dissection. After insertion of the stent, the following results were observed: a) AR improved; b) proximal descending aorta and superior mesenteric arterial flows increased; c) cardiac function improved; and d) the dissecting aortic diameter decreased in the presence of pressure gradient group. From these results, insertion of a stent-graft to treat acute aortic dissection was judged to be effective.

Original languageEnglish
Pages (from-to)89-95
Number of pages7
JournalActa medica Okayama
Issue number2
Publication statusPublished - Apr 1998
Externally publishedYes


  • Acute aortic dissection
  • Blanton's method
  • Endoluminal graft
  • Stent-graft

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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