Effects of fujibitol, a remedy for nasal symptoms of immediate and delayed type allergic reactions

Masanori Kakimoto; Naoyuki Takasugi; Tohru Fuwa; Hiroshi Saito; Yukio Sugimoto; Chiaki Kamei

doi:10.1358/mf.1999.21.5.541913

Effects of fujibitol, a remedy for nasal symptoms of immediate and delayed type allergic reactions

Masanori Kakimoto, Naoyuki Takasugi, Tohru Fuwa, Hiroshi Saito, Yukio Sugimoto, Chiaki Kamei

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

The effects of Fujibitol, a remedy for the nasal symptoms of immediate and delayed type allergic reactions were studied. Fujibitol inhibited active systemic anaphylaxis in mice, heterologous passive cutaneous anaphylaxis (PCA) in rats, Masugi's nephritis in rats and delayed type hypersensitivity induced by picryl chloride in mice, but did not affect homologous PCA or immune complex-induced glomerulonephritis in rats. These results suggested that Fujibitol is effective for treatment of allergy-induced inflammation since IgG and type IV allergic reactions were inhibited.

Original language	English
Pages (from-to)	353-356
Number of pages	4
Journal	Methods and Findings in Experimental and Clinical Pharmacology
Volume	21
Issue number	5
DOIs	https://doi.org/10.1358/mf.1999.21.5.541913
Publication status	Published - Jul 3 1999

Keywords

Antiallergic
Antiinflammatory
Fujibitol
Preparation of crude drugs

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)

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10.1358/mf.1999.21.5.541913

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abstract = "The effects of Fujibitol, a remedy for the nasal symptoms of immediate and delayed type allergic reactions were studied. Fujibitol inhibited active systemic anaphylaxis in mice, heterologous passive cutaneous anaphylaxis (PCA) in rats, Masugi's nephritis in rats and delayed type hypersensitivity induced by picryl chloride in mice, but did not affect homologous PCA or immune complex-induced glomerulonephritis in rats. These results suggested that Fujibitol is effective for treatment of allergy-induced inflammation since IgG and type IV allergic reactions were inhibited.",

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T1 - Effects of fujibitol, a remedy for nasal symptoms of immediate and delayed type allergic reactions

AU - Kakimoto, Masanori

AU - Takasugi, Naoyuki

AU - Fuwa, Tohru

AU - Saito, Hiroshi

AU - Sugimoto, Yukio

AU - Kamei, Chiaki

PY - 1999/7/3

Y1 - 1999/7/3

N2 - The effects of Fujibitol, a remedy for the nasal symptoms of immediate and delayed type allergic reactions were studied. Fujibitol inhibited active systemic anaphylaxis in mice, heterologous passive cutaneous anaphylaxis (PCA) in rats, Masugi's nephritis in rats and delayed type hypersensitivity induced by picryl chloride in mice, but did not affect homologous PCA or immune complex-induced glomerulonephritis in rats. These results suggested that Fujibitol is effective for treatment of allergy-induced inflammation since IgG and type IV allergic reactions were inhibited.

AB - The effects of Fujibitol, a remedy for the nasal symptoms of immediate and delayed type allergic reactions were studied. Fujibitol inhibited active systemic anaphylaxis in mice, heterologous passive cutaneous anaphylaxis (PCA) in rats, Masugi's nephritis in rats and delayed type hypersensitivity induced by picryl chloride in mice, but did not affect homologous PCA or immune complex-induced glomerulonephritis in rats. These results suggested that Fujibitol is effective for treatment of allergy-induced inflammation since IgG and type IV allergic reactions were inhibited.

KW - Antiallergic

KW - Antiinflammatory

KW - Fujibitol

KW - Preparation of crude drugs

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Effects of fujibitol, a remedy for nasal symptoms of immediate and delayed type allergic reactions

Abstract

Keywords

ASJC Scopus subject areas

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