EIN2, a bifunctional transducer of ethylene and stress responses in Arabidopsis

Jose M. Alonso; Takashi Hirayama; Gregg Roman; Saeid Nourizadeh; Joseph R. Ecker

doi:10.1126/science.284.5423.2148

EIN2, a bifunctional transducer of ethylene and stress responses in Arabidopsis

Jose M. Alonso, Takashi Hirayama, Gregg Roman, Saeid Nourizadeh, Joseph R. Ecker

Research output: Contribution to journal › Article › peer-review

973 Citations (Scopus)

Abstract

Ethylene regulates plant growth, development, and responsiveness to a variety of stresses. Cloning of the Arabidopsis EIN2 gene identifies a central component of the ethylene signalng pathway. The amino-terminal integral membrane domain of EIN2 Shows similarity to the disease-related Nramp family of metalion transporters. Expression of the EIN2 CEND is Sufficient to constitutively activate ethylene responses and restores responsiveness to jasmonic acid and paraquat-induced oxygen radicals to mutant plants. EIN2 is thus recognized as a molecular link between previously distinct hormone response pathways. Plants may use a combinatorial mechanism for assessing various stresses by enlisting a common set of signaling molecules.

Original language	English
Pages (from-to)	2148-2152
Number of pages	5
Journal	Science
Volume	284
Issue number	5423
DOIs	https://doi.org/10.1126/science.284.5423.2148
Publication status	Published - Jun 25 1999
Externally published	Yes

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abstract = "Ethylene regulates plant growth, development, and responsiveness to a variety of stresses. Cloning of the Arabidopsis EIN2 gene identifies a central component of the ethylene signalng pathway. The amino-terminal integral membrane domain of EIN2 Shows similarity to the disease-related Nramp family of metalion transporters. Expression of the EIN2 CEND is Sufficient to constitutively activate ethylene responses and restores responsiveness to jasmonic acid and paraquat-induced oxygen radicals to mutant plants. EIN2 is thus recognized as a molecular link between previously distinct hormone response pathways. Plants may use a combinatorial mechanism for assessing various stresses by enlisting a common set of signaling molecules.",

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AU - Alonso, Jose M.

AU - Hirayama, Takashi

AU - Roman, Gregg

AU - Nourizadeh, Saeid

AU - Ecker, Joseph R.

PY - 1999/6/25

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AB - Ethylene regulates plant growth, development, and responsiveness to a variety of stresses. Cloning of the Arabidopsis EIN2 gene identifies a central component of the ethylene signalng pathway. The amino-terminal integral membrane domain of EIN2 Shows similarity to the disease-related Nramp family of metalion transporters. Expression of the EIN2 CEND is Sufficient to constitutively activate ethylene responses and restores responsiveness to jasmonic acid and paraquat-induced oxygen radicals to mutant plants. EIN2 is thus recognized as a molecular link between previously distinct hormone response pathways. Plants may use a combinatorial mechanism for assessing various stresses by enlisting a common set of signaling molecules.

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EIN2, a bifunctional transducer of ethylene and stress responses in Arabidopsis

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