TY - JOUR
T1 - Elderly patient with varicella-zoster virus-associated hemophagocytic syndrome refractory to steroid therapy
AU - Yoshida, Isao
AU - Yoshino, Tadashi
AU - Takeuchi, Makoto
N1 - Copyright:
This record is sourced from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
PY - 2005/11
Y1 - 2005/11
N2 - We experienced a case of virus-associated hemophagocytic syndrome (VAHS) after varicella-zoster virus (VZV) infection. The patient, a 101-year-old man, presented with anemia, thrombocytopenia and jaundice two weeks after successful antiviral treatment for the VZV. Histiocytes were detected in the bone marrow examination (2.2%); however, hepatomegaly and triglycemia remained unobserved throughout the course. Reactivation of VZV was detected serologically. The patient died after five weeks because of persistent cytopenia and liver failure refractory to steroid treatment. An autopsy revealed hemophagocytosis in the bone marrow, lung, spleen and liver.
AB - We experienced a case of virus-associated hemophagocytic syndrome (VAHS) after varicella-zoster virus (VZV) infection. The patient, a 101-year-old man, presented with anemia, thrombocytopenia and jaundice two weeks after successful antiviral treatment for the VZV. Histiocytes were detected in the bone marrow examination (2.2%); however, hepatomegaly and triglycemia remained unobserved throughout the course. Reactivation of VZV was detected serologically. The patient died after five weeks because of persistent cytopenia and liver failure refractory to steroid treatment. An autopsy revealed hemophagocytosis in the bone marrow, lung, spleen and liver.
UR - http://www.scopus.com/inward/record.url?scp=33644894789&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33644894789&partnerID=8YFLogxK
M3 - Article
C2 - 16440810
AN - SCOPUS:33644894789
SN - 0485-1439
VL - 46
SP - 1229
EP - 1232
JO - [Rinshō ketsueki] The Japanese journal of clinical hematology
JF - [Rinshō ketsueki] The Japanese journal of clinical hematology
IS - 11
ER -