TY - GEN
T1 - Electrical acupuncture modifies autonomic balance by resetting the neural arc of arterial baroreflex system
AU - Sugimachi, Masaru
AU - Kawada, Toru
AU - Kamiya, Atsunori
AU - Li, Meihua
AU - Zheng, Can
AU - Sunagawa, Kenji
PY - 2007
Y1 - 2007
N2 - Contribution of abnormal cardiovascular regulation to the maintenance and progression of heart failure has been repeatedly demonstrated. Besides the current therapeutic modalities, development of an additional therapeutic strategy is needed. We have been developing a bionic system, an artificial device designed for integration into native physiological systems. By communicating with the physiological regulatory system, we tried to not only restore lost function but also correct abnormal function. We have already shown that modification of autonomic balance by direct electrical vagal stimulation has inhibited cardiac remodeling, and improved survival in rats. Because the benefit of the correction of autonomic balance would be greatly enhanced if available by a less invasive method, we examined the possibility of modifying the autonomic balance by electrical acupuncture. The results indicated that electrical acupuncture resets the neural arc of the arterial baroreflex (SNA response range decreases from 144.0±35.0 to 112.6±9.2, p<0.005) and is able to attenuate sympathetic nerve activity.
AB - Contribution of abnormal cardiovascular regulation to the maintenance and progression of heart failure has been repeatedly demonstrated. Besides the current therapeutic modalities, development of an additional therapeutic strategy is needed. We have been developing a bionic system, an artificial device designed for integration into native physiological systems. By communicating with the physiological regulatory system, we tried to not only restore lost function but also correct abnormal function. We have already shown that modification of autonomic balance by direct electrical vagal stimulation has inhibited cardiac remodeling, and improved survival in rats. Because the benefit of the correction of autonomic balance would be greatly enhanced if available by a less invasive method, we examined the possibility of modifying the autonomic balance by electrical acupuncture. The results indicated that electrical acupuncture resets the neural arc of the arterial baroreflex (SNA response range decreases from 144.0±35.0 to 112.6±9.2, p<0.005) and is able to attenuate sympathetic nerve activity.
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U2 - 10.1109/IEMBS.2007.4353546
DO - 10.1109/IEMBS.2007.4353546
M3 - Conference contribution
C2 - 18003212
AN - SCOPUS:57649228549
SN - 1424407885
SN - 9781424407880
T3 - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
SP - 5334
EP - 5337
BT - 29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07
T2 - 29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07
Y2 - 23 August 2007 through 26 August 2007
ER -