Electro-reductive cyclization of aryl halides promoted by fluorene derivatives

Koichi Mitsudo, Yumiko Nakagawa, Jun Ichi Mizukawa, Hideo Tanaka, Ryoichi Akaba, Takahiro Okada, Seiji Suga

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)


In the presence of fluorene derivatives, the electro-reduction of aryl chlorides, bromides, and iodides bearing an ethylene moiety proceeded smoothly to afford the corresponding cyclized products. Noteworthy is that aryl chlorides, which have more negative reduction potential than aryl bromides and iodides, exhibited high reactivity in the reaction, and the corresponding five-membered and six-membered cyclized products were obtained in good to high yields. Mechanistic study suggests that the electro-reduction of fluorene derivatives was essential for the reactions, indicating that they work as a mediator.

Original languageEnglish
Pages (from-to)444-449
Number of pages6
JournalElectrochimica Acta
Publication statusPublished - Nov 1 2012


  • Electro-reduction
  • Fluorene
  • Mediator
  • Radical cyclization
  • Reductive cyclization

ASJC Scopus subject areas

  • General Chemical Engineering
  • Electrochemistry


Dive into the research topics of 'Electro-reductive cyclization of aryl halides promoted by fluorene derivatives'. Together they form a unique fingerprint.

Cite this