Electroclinical study of localization-related epilepsies in early infancy

Iori Ohmori, Yoko Ohtsuka, Eiji Oka, Tomoyuki Akiyama, Shunsuke Ohtahara

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)


To clarify the characteristics of localization-related epilepsies in early infancy, we performed an electroclinical study of 28 epileptic patients whose first seizures occurred before 6 months of age. The patients were retrospectively divided into two groups: the seizure-controlled group (8 patients) and the refractory group (20 patients). The seizure-controlled group included the patients whose seizures were suppressed within 1 year after onset; the refractory group included all other patients. The characteristics of the refractory group were as follows: (1) most patients had serious underlying pathologies; (2) the seizure type in most cases was simple partial seizure or complex partial seizure without secondary generalization; (3) the interictal EEG showed focal abnormalities and severe dysrhythmia on the basic pattern associated with multifocal spikes in most cases; and (4) in some patients, West syndrome developed after localization- related epilepsies and generalized seizures appeared later in some cases.

Original languageEnglish
Pages (from-to)131-136
Number of pages6
JournalPediatric Neurology
Issue number2
Publication statusPublished - Feb 1997

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Neurology
  • Developmental Neuroscience
  • Clinical Neurology


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