Epilepsy

Katsuhiro Kobayashi, Tomoyuki Akiyama, Cristina Go

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Epilepsy is defined as a disorder of the braincharacterized by an enduring predisposition to generate epileptic seizures. An epileptic seizure is a transient occurrence of signs and/or symptoms due to abnormal excessive or synchronous neuronal activity in the brain that is expressed by epileptic discharges in electroencephalogram (EEG). The definition of epilepsy requires any of the following conditions: 1) at least two unprovoked seizures; 2) one unprovoked seizure and likely subsequent recurrence of similar seizures; 3) diagnosis of an epilepsy syndrome, which is defined based on combinations of clinical and EEG characteristics.

Original languageEnglish
Title of host publicationHuman Pathobiochemistry
Subtitle of host publicationFrom Clinical Studies to Molecular Mechanisms
PublisherSpringer Singapore
Pages295-310
Number of pages16
ISBN (Electronic)9789811329777
ISBN (Print)9789811329760
DOIs
Publication statusPublished - Jan 1 2019

Keywords

  • Antiepileptic drug
  • Development
  • Electroencephalogram
  • Epilepsy syndrome
  • Seizure

ASJC Scopus subject areas

  • General Medicine
  • General Biochemistry,Genetics and Molecular Biology

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