Evaluation of developing damages in fallopian tubes infected with Chlamydia trachomatis: Analysis of waveform in tubal insufflation

Chlamydial infection leads to dysfunction of fallopian tubes and sterility. We investigated tubal damage caused by Chlamydial infection by analyzing waveforms in tubal insufflation test. After serological test for Chlamydia trachomatis tubal insufflation test was performed in 102 patients. We measured pressure of the initial peak (Pi), and mean pressure of steady state (Ps), and mean amplitude of steady state (As). Patients were divided into three groups; group A (IgA (-) IgG (-)), group B (IgA (+) IgG (-), or IgA (+) IgG (+): recent infection) and group C (IgA (-) IgG (+): past infection). 1. Both average Ps and average Ps/Pi ratio in group B were lower than those in group A. 2. Average Pi in group C was higher than that in group A. Average Ps/Pi ratio in group C was lower than that in group A. 3. Patients with decreased Ps/Pi ratio (less than 0.6) had low pregnancy rate. Analysis of waveforms in tubal insufflation test was useful to evaluate tubal damage. Patients who have abnormality in parameters (Pi, Ps, and Ps/Pi ratio) have low pregnancy rate. Further examination and treatment of fallopian tubes should be performed for these patients.