In this immunohistochemical examination, the expression of Notch1 peptide was detected in neo-plastic cells in a case of osteosarcoma of the maxilla of a 31 -year-old Indonesian male patient. Notch1 peptide appeared in the cytoplasm of neoplastic cells of comparatively well-differentiated areas of the osteosarcoma, an osteoblastic area containing osteoid and/or immature bone tissues. The results suggest that Notch1 is closely related to cytological differentiation of acquisition of cytological characteristics in neoplastic cells of osteosarcoma.
|Number of pages||3|
|Journal||European journal of medical research|
|Publication status||Published - 2004|
- Cytological characteristics
- Morphogenesis regulation factor
- Notch1 peptide
ASJC Scopus subject areas