Abstract
In this immunohistochemical examination, the expression of Notch1 peptide was detected in neo-plastic cells in a case of osteosarcoma of the maxilla of a 31 -year-old Indonesian male patient. Notch1 peptide appeared in the cytoplasm of neoplastic cells of comparatively well-differentiated areas of the osteosarcoma, an osteoblastic area containing osteoid and/or immature bone tissues. The results suggest that Notch1 is closely related to cytological differentiation of acquisition of cytological characteristics in neoplastic cells of osteosarcoma.
| Original language | English |
|---|---|
| Pages (from-to) | 533-535 |
| Number of pages | 3 |
| Journal | European journal of medical research |
| Volume | 9 |
| Issue number | 11 |
| Publication status | Published - 2004 |
Keywords
- Cyto-differentiation
- Cytological characteristics
- Immunohistochemistry
- Morphogenesis
- Morphogenesis regulation factor
- Notch1 peptide
- Osteosarcoma
ASJC Scopus subject areas
- Medicine(all)