Fabrication of chelate-setting cement using silicon-substituted hydroxyapatite and its property

Y. Nakashima, M. Honda, T. Konishi, M. Mizumoto, M. Aizawa

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    We have developed novel hydroxyapatite (HAp) cement, "chelate-setting HAp cement" on the basis of chelate bonding of inositol hexaphosphate (IP6). In order to create the cement with enhanced bioactivity, we used a silicon-substituted hydroxyapatite (Si-HAp) as a starting material instead of pure HAp powder. The Si-HAp powders were prepared via an aqueous precipitation reaction and surface-modified with IP6 (IP6-Si-HAp). The Si-HAp were synthesized with desired Si contents (0, 0.4, 0.8, 1.6, and 2.4 mass%). Regardless of the amount of Si, the XRD patterns and FT-IR spectra of the powders were similar to each other. Additionally, chemical composition of Si-HAp powders were the almost same as the nominal one. The substitution of Si resulted in a decrease in the a-axis and increase in the c-axis of unit cell of HAp. While, the compressive strength of IP6-Si-HAp cements was higher than that of Si-HAp cements. These results suggest that surface-modification of any powders with IP6 is effective for enhancement of mechanical property. Comparison of mechanical property between HAp and Si-HAp cement specimens revealed that the substitution of lower levels of Si into0 HAp lattice did not greatly influence compressive strength. However, the substitution of high dose of Si (over 2.4 mass%) reduced the compressive strength. Therefore, to fabricate the chelate-setting cements with enhanced bioactivity, it is necessary to control the amount of Si.

    Original languageEnglish
    Title of host publicationBioceramics 23
    PublisherTrans Tech Publications Ltd
    Pages370-374
    Number of pages5
    ISBN (Print)9783037852552
    DOIs
    Publication statusPublished - 2012
    Event23rd Symposium and Annual Meeting of International Society for Ceramics in Medicine, ISCM 2011 - Istanbul, Turkey
    Duration: Nov 6 2011Nov 9 2011

    Publication series

    NameKey Engineering Materials
    Volume493-494
    ISSN (Print)1013-9826
    ISSN (Electronic)1662-9795

    Other

    Other23rd Symposium and Annual Meeting of International Society for Ceramics in Medicine, ISCM 2011
    Country/TerritoryTurkey
    CityIstanbul
    Period11/6/1111/9/11

    Keywords

    • Cement
    • Hydroxyapatite
    • Inositol phosphate
    • Silicon-substituted hydroxyapatite

    ASJC Scopus subject areas

    • General Materials Science
    • Mechanics of Materials
    • Mechanical Engineering

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