Factors affecting the quality of life of patients with painful spinal bone metastases

Yoshiteru Akezaki, Eiji Nakata, Masato Kikuuchi, Shinsuke Sugihara, Yoshimi Katayama, Haruki Katayama, Masanori Hamada, Toshifumi Ozaki

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


This study examined changes in the quality of life (QOL), as well as the factors affecting QOL, among patients with painful spinal bone metastases without paralysis for 1 month after radiotherapy. Methods: This study included 79 participants (40 male and 39 female; median age, 65 (42–88) years) who had undergone radiotherapy for painful spinal bone metastases without paralysis. Patients’ age, sex, activities of daily living (Barthel index), pain, spinal instability (spinal instability neoplastic score [SINS]), and QOL (EORTC QLQ-C30) were investigated. Results: Having an unstable SINS score was a positive factor for global health status (p < 0.05). The improvement in activities of daily living and response to pain were positive factors for physical function (p < 0.05). A positive effect on emotional function was confirmed among female patients (p < 0.05). Conclusion: Engaging in rehabilitation along with radiotherapy leads to improvements in QOL for patients with spinal bone metastases.

Original languageEnglish
Article number1499
JournalHealthcare (Switzerland)
Issue number11
Publication statusPublished - Nov 2021


  • Activities of daily living
  • Pain
  • Quality of life
  • Radiotherapy
  • Spinal bone metastases

ASJC Scopus subject areas

  • Health Informatics
  • Health Policy
  • Health Information Management
  • Leadership and Management


Dive into the research topics of 'Factors affecting the quality of life of patients with painful spinal bone metastases'. Together they form a unique fingerprint.

Cite this