Familial spinal arachnoiditis with secondary syringomyelia: Clinical studies and MRI findings

Makiko Nagai, Ryo Sakuma, Masashi Aoki, Koji Abe, Yasuto Itoyama

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


We report the clinical and MRI findings of two patients with familial spinal arachnoiditis. Although their initial symptoms were various, they both showed spastic paraparesis and sensory disturbance below the thoracic level. Cytokines and WBC in the CSF were studied, but they were not elevated at all. The spinal magnetic resonance images of each showed extensive arachnoiditis and a cystic structure. The other impressive features included: (i) an enhancement within the thickened arachnoid and an adhesion between the spinal cord and the dura mater, (ii) deformation of the thoracic cord where the arachnoid adhered, and (iii) secondary syrinx formation. Laminectomy may have an adverse outcome for such patients. (C) 2000 Elsevier Science B.V.

Original languageEnglish
Pages (from-to)60-64
Number of pages5
JournalJournal of the neurological sciences
Issue number1
Publication statusPublished - Aug 1 2000
Externally publishedYes


  • Arachnoiditis
  • Autosomal dominant
  • Cytokines
  • Familial
  • Syringomyelia

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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