Four cases of desquamative esophagitis occurring after hematopoietic stem cell transplantation

Masaya Iwamuro, Daisuke Ennishi, Ken Ichi Matsuoka, Takehiro Tanaka, Shotaro Okanoue, Yuka Obayashi, Hiroyuki Sakae, Yoshiro Kawahara, Hiroyuki Okada

Research output: Contribution to journalArticlepeer-review


We herein report four patients with desquamative esophagitis that developed one to nine days after peripheral blood stem cell transplantation (PBSCT). Three patients underwent allogeneic PBSCT for leukemia, and the other underwent autologous PBSCT for pineoblastoma. Esophagogastroduodenoscopy revealed mucosal sloughing and fresh blood in the esophagus. Fasting and intravenous proton pump inhibitor therapy in addition to blood transfusion improved the esophageal lesions within five to seven days in three patients. These cases indicate that desquamative esophagitis can occur in patients who receive hematopoietic stem cell transplantation. Although blood transfusions may be required, it can be resolved within seven days.

Original languageEnglish
Pages (from-to)3015-3022
Number of pages8
JournalInternal Medicine
Issue number23
Publication statusPublished - Dec 1 2020


  • Desquamative esophagitis
  • Esophagitis dissecans superficialis
  • Peripheral blood stem cell transplantation
  • Sloughing esophagitis

ASJC Scopus subject areas

  • Internal Medicine


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