Frequent Detection of Hepatitis C Virus US Strain in Japanese Hemophiliacs

Makoto Hijikata, Nobuyuki Kato, Shigehisa Mori, Yuko Ootsuyama, Masanori Nakagawa, Takashi Sugimura, Showgo Ohkoshi, Hideo Kojima, Takashi Meguro, Masashi Taki, Shigenobu Takayama, Kaneo Yamada, Kunitada Shimotohno

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)


Hemophiliacs have been found to be at high risk of hepatitis. Hemophiliacs in Japan receive imported clotting factors as well as domestic ones. Recently we found that hepatitis C virus (HCV) could be classified into at least two types, HCV‐US and HCV‐J, depending on the nucleotide sequence. We analyzed the nucleotide sequences of virus RNAs from the plasma of patients with hemophilia A or B and found HCV‐US in 3 of 4 Japanese hemophiliacs examined.

Original languageEnglish
Pages (from-to)1195-1197
Number of pages3
JournalJapanese Journal of Cancer Research
Issue number12
Publication statusPublished - Dec 1990
Externally publishedYes


  • Clotting factors
  • Hemophilia
  • Hepatitis C virus
  • Non‐A
  • Transfusion
  • non‐B hepatitis

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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