TY - JOUR
T1 - Functional evaluation of mineral trioxide aggregate cement with choline dihydrogen phosphate
AU - Tabira, Kazuhisa
AU - Kajimoto, Noboru
AU - Minamisawa, Hirogo
AU - Sato, Taira
AU - Maruta, Michito
AU - Oka, Kyoko
AU - Kataoka, Takuya
AU - Yoshioka, Tomohiko
AU - Hayakawa, Satoshi
AU - Tsuru, Kanji
N1 - Publisher Copyright:
© 2023, Japanese Society for Dental Materials and Devices. All rights reserved.
PY - 2023
Y1 - 2023
N2 - To improve the cytocompatibility of mineral trioxide aggregate (MTA) cement and its ability for reparative dentin formation, the effect of adding choline dihydrogen phosphate (CDHP), which is reported to be biocompatible, to MTA cement was investigated. The L929 cell proliferation showed that the addition of CDHP improved cell viability. The addition of CDHP shortened the setting time of MTA cement, with a significant decrease in consistency above 0.4 g/mL. Diametral tensile strength of the set cement was improved by the addition of 0.4 g/mL CDHP. Solubility was judged to be within the range of clinical application. The spontaneous precipitation of low crystalline hydroxyapatite was examined by immersing the set cement in phosphate buffer saline, and it was found that the ability of the cement with 0.4 g/mL of CDHP was significantly improved compared with that of the cement without CDHP.
AB - To improve the cytocompatibility of mineral trioxide aggregate (MTA) cement and its ability for reparative dentin formation, the effect of adding choline dihydrogen phosphate (CDHP), which is reported to be biocompatible, to MTA cement was investigated. The L929 cell proliferation showed that the addition of CDHP improved cell viability. The addition of CDHP shortened the setting time of MTA cement, with a significant decrease in consistency above 0.4 g/mL. Diametral tensile strength of the set cement was improved by the addition of 0.4 g/mL CDHP. Solubility was judged to be within the range of clinical application. The spontaneous precipitation of low crystalline hydroxyapatite was examined by immersing the set cement in phosphate buffer saline, and it was found that the ability of the cement with 0.4 g/mL of CDHP was significantly improved compared with that of the cement without CDHP.
KW - Choline dihydrogen phosphate (CDHP)
KW - Cytocompatibility
KW - Low crystalline hydroxyapatite
KW - Mineral trioxide aggregate (MTA)
KW - Reparative dentin
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U2 - 10.4012/dmj.2022-283
DO - 10.4012/dmj.2022-283
M3 - Article
C2 - 37121734
AN - SCOPUS:85166442340
SN - 0287-4547
VL - 42
SP - 485
EP - 492
JO - Dental materials journal
JF - Dental materials journal
IS - 4
M1 - dmj/2022-283
ER -