Gene Expression Profiling and Differentiation of Immortalized Human Mesenchymal Stem Cells

Hiroki Mori; Junko Kato; Hirotami Matsuo; Tohru Nakanishi; Naoya Kobayashi; Yoshikazu Kosaka; Takashi Oka; Noriaki Tanaka

doi:10.2485/jhtb.14.267

Gene Expression Profiling and Differentiation of Immortalized Human Mesenchymal Stem Cells

Hiroki Mori, Junko Kato, Hirotami Matsuo, Tohru Nakanishi, Naoya Kobayashi, Yoshikazu Kosaka, Takashi Oka, Noriaki Tanaka

Research output: Contribution to journal › Article › peer-review

Abstract

Human bone marrow mesenchymal stem cells (hMSCs), tissue-derived stem cells, have the ability to differentiate into adipocytes, osteoblasts and chondrocytes, leading to attempt to apply these stem cells for regeneration of bone and cartilage. To address pluripotency of hMSCs, we analyzed gene expression profiles of several immortalized hMSCs with DNA chips that nearly covers the whole human genes. We isolated some factors that possibly relate to pluripotency of these hMSCs.

Original language	English
Pages (from-to)	267-268
Number of pages	2
Journal	Journal of Hard Tissue Biology
Volume	14
Issue number	2
DOIs	https://doi.org/10.2485/jhtb.14.267
Publication status	Published - Jan 2005

ASJC Scopus subject areas

Medicine (miscellaneous)
Biochemistry
Biomaterials
Orthopedics and Sports Medicine
Dentistry(all)
Cell Biology

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abstract = "Human bone marrow mesenchymal stem cells (hMSCs), tissue-derived stem cells, have the ability to differentiate into adipocytes, osteoblasts and chondrocytes, leading to attempt to apply these stem cells for regeneration of bone and cartilage. To address pluripotency of hMSCs, we analyzed gene expression profiles of several immortalized hMSCs with DNA chips that nearly covers the whole human genes. We isolated some factors that possibly relate to pluripotency of these hMSCs.",

author = "Hiroki Mori and Junko Kato and Hirotami Matsuo and Tohru Nakanishi and Naoya Kobayashi and Yoshikazu Kosaka and Takashi Oka and Noriaki Tanaka",

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AU - Mori, Hiroki

AU - Kato, Junko

AU - Matsuo, Hirotami

AU - Nakanishi, Tohru

AU - Kobayashi, Naoya

AU - Kosaka, Yoshikazu

AU - Oka, Takashi

AU - Tanaka, Noriaki

PY - 2005/1

Y1 - 2005/1

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Gene Expression Profiling and Differentiation of Immortalized Human Mesenchymal Stem Cells

Abstract

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