Gestational Outcomes and Birth Weight in Japanese Women at the Upper and Lower limits of the Normal BMI range

Yoko Ishioka, Hiroyuki Yamashita, Kinya Hamaguchi, Yoshitaka Kuwahara, Kaoru Nakamura, Mikiya Nakatsuka

Research output: Contribution to journalArticlepeer-review


To examine the outcome of gestational blood pressure and birth weight in women with normal pre-pregnancy BMI (18.5-25 kg/m2) who are at the lower and upper limits of this range, i.e., slightly underweight or slightly overweight. Overall, 2,038 Japanese women with low -risk who had delivered during January 2014–December 2016 were classified according to their pre-pregnancy BMI: underweight (< 18.5 kg/m2), slightly underweight (18.5≤BMI<21 kg/m2), normal (21≤BMI<23 kg/m2), slightly overweight (23≤BMI<25 kg/m2) and overweight (≤ 25 kg/m2). Their blood pressure during each trimester and birth weight was evaluated. The slightly overweight group showed a significantly higher blood pressure than the underweight and slightly underweight groups. Birth weight was lower in the slightly underweight than in the slightly overweight group (p<0.01). The incidence rate of “heavy for dates” (HFD) infants was significantly higher in the slightly overweight and overweight groups than in the other groups (p<0.05 and p<0.01, respectively). Weight gain of < 7 kg significantly increased the rate of “light for dates” (LFD) infants, while a weight gain of ≥13 kg significantly increased the rate of HFD infants (p<0.05 and p<0.01, respectively). Blood pressure during pregnancy was associated with pre-pregnancy BMI. The birth weight of infants of low-risk pregnant women is affected by both pre-pregnancy BMI and gestational weight gain.

Original languageEnglish
Pages (from-to)519-526
Number of pages8
JournalActa medica Okayama
Issue number5
Publication statusPublished - 2022


  • Birth weight
  • Blood pressure
  • Normal body weight
  • Pregnancy pre-pregnancy bmi

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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