Glutathione Peroxidase-Like Catalytic Activities of Ion-Exchange Resins Modified with Metalloporphyrins

Akimasa Iwado; Masaki Mifune; Rumiko Harada; Takashi Mukuno; Noriko Motohashi; Yutaka Saito

doi:10.2116/analsci.14.515

Glutathione Peroxidase-Like Catalytic Activities of Ion-Exchange Resins Modified with Metalloporphyrins

Akimasa Iwado, Masaki Mifune, Rumiko Harada, Takashi Mukuno, Noriko Motohashi, Yutaka Saito

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

Some of the ion-exchange resins modified with metalloporphyrins have been found to exhibit glutathione-peroxidase (GSHPx)-like catalytic activities for hydrogen peroxide and cumene hydroperoxide in the oxidative reaction of glutathione to disulfide. In particular, the anion-exchange resin modified with Mn(III)-tetrakis(sulfophenyl)porphine (Mn-TSPP_r) exhibited stronger activity than GSHP_x, and hence Mn-TSPP_r was expected to be a good mimesis in place of GSHP_x or immobilized GSHP_x for the determination of peroxide.

Original language	English
Pages (from-to)	515-518
Number of pages	4
Journal	Analytical Sciences
Volume	14
Issue number	3
DOIs	https://doi.org/10.2116/analsci.14.515
Publication status	Published - 1998

Keywords

Cumene hydroperoxide
Glutathione-peroxidase-like activity
Hydrogen peroxide
Ion-exchange resin modified with metalloporphyrin

ASJC Scopus subject areas

Analytical Chemistry

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10.2116/analsci.14.515

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abstract = "Some of the ion-exchange resins modified with metalloporphyrins have been found to exhibit glutathione-peroxidase (GSHPx)-like catalytic activities for hydrogen peroxide and cumene hydroperoxide in the oxidative reaction of glutathione to disulfide. In particular, the anion-exchange resin modified with Mn(III)-tetrakis(sulfophenyl)porphine (Mn-TSPPr) exhibited stronger activity than GSHPx, and hence Mn-TSPPr was expected to be a good mimesis in place of GSHPx or immobilized GSHPx for the determination of peroxide.",

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T1 - Glutathione Peroxidase-Like Catalytic Activities of Ion-Exchange Resins Modified with Metalloporphyrins

AU - Iwado, Akimasa

AU - Mifune, Masaki

AU - Harada, Rumiko

AU - Mukuno, Takashi

AU - Motohashi, Noriko

AU - Saito, Yutaka

PY - 1998

Y1 - 1998

N2 - Some of the ion-exchange resins modified with metalloporphyrins have been found to exhibit glutathione-peroxidase (GSHPx)-like catalytic activities for hydrogen peroxide and cumene hydroperoxide in the oxidative reaction of glutathione to disulfide. In particular, the anion-exchange resin modified with Mn(III)-tetrakis(sulfophenyl)porphine (Mn-TSPPr) exhibited stronger activity than GSHPx, and hence Mn-TSPPr was expected to be a good mimesis in place of GSHPx or immobilized GSHPx for the determination of peroxide.

AB - Some of the ion-exchange resins modified with metalloporphyrins have been found to exhibit glutathione-peroxidase (GSHPx)-like catalytic activities for hydrogen peroxide and cumene hydroperoxide in the oxidative reaction of glutathione to disulfide. In particular, the anion-exchange resin modified with Mn(III)-tetrakis(sulfophenyl)porphine (Mn-TSPPr) exhibited stronger activity than GSHPx, and hence Mn-TSPPr was expected to be a good mimesis in place of GSHPx or immobilized GSHPx for the determination of peroxide.

KW - Cumene hydroperoxide

KW - Glutathione-peroxidase-like activity

KW - Hydrogen peroxide

KW - Ion-exchange resin modified with metalloporphyrin

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Glutathione Peroxidase-Like Catalytic Activities of Ion-Exchange Resins Modified with Metalloporphyrins

Abstract

Keywords

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